Data Centers that implement Software-Defined Networks (SDN) are not required to employ the Address Resolution Protocol (ARP), but network hosts do. Therefore, there is a need to support this protocol without modifying the intrinsic functionality of the SDN controller. In this work, four strategies for handling ARP are evaluated using an SDN and OpenFlow rules. The strategies include disabling ARP at the host level, using static MAC addresses, introducing a fake gateway, and generating ARP replies using OpenFlow flows. To our knowledge, nobody has tested and compared the main characteristics and advantages offered by these four strategies. Experimental evaluation was conducted on a real SDN network and complemented with similar experiments using Mininet. Performance was assessed using metrics such as ping response time, address resolution response time, jitter, and packet loss ratio. The results show that OpenFlow-based ARP replies provide a good balance in terms of scalability, performance, and configuration effort. This strategy achieved the lowest average ping response time (0.641 ms) and ARP response time (0.6188 ms), while avoiding the manual configuration requirements of static approaches.