Background: Noninvasive energy‐based device (NI‐EBD) aesthetic procedures has recently gained widespread usage for treating various skin conditions, enhancing skin texture and performing rejuvenation‐related procedures. However, practically all NI‐EBD procedures result in variable degrees of damage to the skin barrier, inducing pathological and physiological processes such as oxidative stress and inflammation, and only a small percentage of individuals possess the innate ability to restore it.Objective: To introduce the concept of integrated skincare and establish standardized operational procedures for perioperative integrated skincare, and furnish a theoretical basis for clinical diagnosis and treatment performed by professional medical aestheticians.Methods: The author leveraged domestic and international guidelines, clinical practice expertise and evidence‐based research, adapting them to suit the specific circumstances in China.Results: The consensus were provided four parts, including concept and essence of integrated skincare, integrated skincare significance during the perioperative phase of NI‐EBD procedures, active ingredients and functions of effective skincare products, standardized perioperative skincare procedure for NI‐EBD procedures and precautions. For the standardized perioperative skincare procedure, four recommendations were listed according to different stages during NI‐EBD procedures.Conclusion: These recommendations create the ‘Expert Consensus on Perioperative Integrated Skincare for Noninvasive Energy‐Based Device Aesthetic Procedures in Clinical Practice in China’.
5 September 2024 in Journal of Cosmetic Dermatology
Background: The picosecond 755‐nm alexandrite laser and topical tranexamic acid (TA) have shown promise in treating melasma.Aim: This aim of this study was to evaluate the efficacy and safety of combining to a picosecond 755‐nm alexandrite laser combined with topical TA for melasma treatment.Patients and Methods: Forty‐eight patients’ facial halves with bilateral symmetrical melasma were randomized to receive either topical TA and picosecond laser treatment or laser monotherapy. All patients received three consecutive picosecond laser treatment sessions at 4‐week intervals, and additional one side facial received topical TA treatment twice daily until 4 weeks after the third treatments. Efficacy was assessed using the Modified Melasma Area and Severity Index (mMASI) score, VISIA (Canfield, USA) red area feature counts, and average pore volume as measured by Antera 3D®. Patient satisfaction was evaluated through questionnaires.Results: Thirty‐five patients completed the study. Post‐treatment, mMASI scores and VISIA red area feature counts were lower in combination therapy halves and laser monotherapy halves, and average melanin level was lower in the combination therapy halves (p < 0.05). Comparisons between the combination therapy halves and laser monotherapy halves after the third treatment revealed significant differences in mMASI scores, melanin levels, and VISIA red area feature counts (p < 0.05). After treatment, patient satisfaction rates in the combination therapy halves and monotherapy halves was 71.4% and 54.3%, respectively (p < 0.05). No obvious adverse effects were observed in the combination therapy halves; whereas, 10.42% (5/48) of participants in the laser monotherapy halves experienced temporary pigmentation, which resolved within 3 months.Conclusion: The picosecond 755‐nm alexandrite laser, when used independently and in combination with topical TA, has been proven to be effective in the improvement of melasma. However, the combined treatment approach showed a more pronounced improvement in melasma symptoms, with higher patient satisfaction, and was associated with a lower incidence of adverse effects. These findings strongly support that integrating topical TA with picosecond laser therapy as a superior therapeutic strategy for melasma management.Clinical Trial Registration: Chinese Clinical Trial Registry: ChiCTR2200057771.
17 December 2025 in International Journal of Dermatology