Highly saturated structural colors are crucial for the micro-nanophotonic displays. However, achieving Schrödinger’s red pixels remains a challenge due to the difficulty in suppressing higher-order resonances in the blue-green wavelength band. In this paper, we utilize the TuRBO algorithm for global physical parameter optimization of periodic ${\mathrm{Sb}}_2{\mathrm{S}}_3$ nanopillar metasurface structures to realize the high-saturation red. Based on the intrinsic dispersion characteristics of ${\mathrm{Sb}}_2{\mathrm{S}}_3$ characterized by high extinction coefficients in the blue-green wavelength band, the high-saturation Schrödinger’s red that surpasses the Adobe RGB boundary has been produced successfully. The calculated results show that after 45 iterations, the structure achieves gradient refractive index matching, aligning the intrinsic dispersion of ${\mathrm{Sb}}_2{\mathrm{S}}_3$ with the ideal reflection spectrum of Schrödinger’s red pixels, thereby effectively suppressing higher-order resonances in the blue-green wavelength band. Ultimately, an ultra-high saturation red is achieved with CIE coordinates of (0.6507, 0.3043) in the CIE chromaticity space.