Sağlık uygulamalarının kolaylaştırılması, ölçülebilir, karşılaştırılabilir ve ulaşılabilir hale gelmesi hedefi, bu sektörde dijital bir dönüşümü gerekli kılmıştır. Randevu sistemlerinden, görüntüleme sistemlerine, ilaç takibinden, hasta bulgularının takibine kadar birçok konuda hem devlet kurumları hem de özel girişimler çeşitli uygulamalar geliştirmektedir. Cep telefonlarıyla uyumlu kullanılabilen bu uygulamalar, insanların teknoloji okur-yazarlığının da artmasıyla gün geçtikçe daha çok kullanılmaya ve benimsenmeye başlamıştır. Sektörün paydaşlarının bu uygulamalardan haberdar olması, amaçlarına uygun kullanması ile daha büyük kitlelere ulaşılacağı düşünülmektedir. Sağlık sektöründe kullanılacak mobil uygulama geliştirilmesinde uygun bir saha araştırması, ihtiyaçların belirlenmesi, profesyonellerin talepleri, kullanışlılık gibi detaylar dikkate alınmalıdır. Daha önce geliştirilen uygulamaların başarısız olanlarının nedenleri incelenmeli, başarılı olanların özellikleri de yeni tasarımlara taşınmalıdır. Bu çalışmada literatürde, internet sitelerinde, Google Play ve IOS uygulama marketlerinde bulunan sağlık uygulamalarının derlenmesi amaçlanmıştır.

Background: Respiratory dysfunction is common after stroke and may negatively affect functional recovery. Inspiratory muscle training (IMT) has been proposed to enhance diaphragmatic function and activity performance in this population. Objective: To investigate the effects of IMT on diaphragm function and activity performance in patients with subacute ischemic stroke. Methods : In this randomized controlled, single-blind trial, 26 patients with subacute ischemic stroke (>1 month post-onset) were randomly allocated to an intervention group (IG, n = 13) or control group (CG, n = 13). Both groups received standard neurorehabilitation, aerobic training, and the Active Cycle of Breathing Technique (ACBT). The IG additionally underwent IMT, 5 days per week for 6 weeks (30 sessions). Assessments included maximal inspiratory and expiratory pressures (MIP, MEP), diaphragmatic thickness (Ti, Te) and excursion via ultrasonography, 6-minute walk test (6MWT), and Canadian Occupational Performance Measure (COPM). Results: Twenty-two participants completed the study (IG = 11; CG = 11). Significant within-group improvements were observed in both groups for MIP, MEP, Ti, TF, excursion, 6MWT, and COPM scores ( P < .05). Between-group analyses showed significantly greater improvements in the IG for ΔMIP ( P < .001), ΔMEP ( P = .003), affected-side ΔTi ( P = .007), ΔTF ( P = .008), and Δexcursion ( P = .005). No significant differences were found for 6MWT and COPM ( P > .05). Conclusions: IMT effectively improves respiratory muscle strength, diaphragmatic thickness, and excursion in subacute ischemic stroke and may be a valuable addition to post-stroke rehabilitation programs. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT06210516.

Purpose: Knee osteoarthritis is one of the leading causes of chronic musculoskeletal pain and disability worldwide. Although intra-articular ozone therapy has demonstrated analgesic effects, the optimal concentration for maximizing pain relief while preserving functional improvement remains uncertain. Our aim is to determine whether different low-dose ozone protocols differ in their ability to reduce pain and improve functional performance in patients with knee osteoarthritis. Patients and Methods: This retrospective comparative study included 45 patients aged 40– 80 years with Kellgren–Lawrence grade II–III knee osteoarthritis. Patients were retrospectively classified into three groups according to the ozone protocol documented in their medical records: 1 μg/mL, 5 μg/mL, and 10 μg/mL, with 15 patients in each group. All patients received intra-articular ozone injections once weekly for 3 consecutive weeks. Outcomes were assessed at baseline and at week 4 using the Visual Analogue Scale (VAS), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the 2-minute walking test. Results: The study included 45 patients, 7 men and 38 women, with a mean age of 59.62 ± 8.08 years. VAS, WOMAC pain, WOMAC physical function, and WOMAC total scores improved significantly in all three groups after treatment. WOMAC stiffness scores improved numerically in all groups but reached statistical significance only in the 5 μg/mL group. No significant between-group differences were found for changes in pain, stiffness, physical function, or total scores. The increase in 2-minute walking test distance was significantly greater in the 1 μg/mL group than in the 10 μg/mL group. No adverse events were documented in any group. Conclusion: Intra-articular ozone therapy was associated with short-term improvements in pain and functional outcomes in patients with knee osteoarthritis, with generally comparable results across the ozone concentrations evaluated. Because of the retrospective design, causal conclusions cannot be drawn, and the difference favoring the lowest concentration in walking distance should be considered exploratory. Prospective studies with larger sample sizes and longer follow-up are needed to confirm these findings.

Background: Children with autism spectrum disorder (ASD) often show atypical sensory processing and reduced play participation, and their mothers frequently report elevated anxiety. However, maternal anxiety symptoms, sensory processing, and children’s play performance and playfulness have rarely been examined together, and the factors independently associated with maternal anxiety symptoms have not yet been clarified. Objective: This study examined relationships between maternal anxiety symptoms and children’s sensory processing, play performance, and playfulness in children with ASD aged 4–6 years, and identified factors independently associated with maternal anxiety symptoms. Method: In this cross-sectional study, 58 mother–child dyads were recruited from a special education center in Istanbul, Türkiye. Maternal anxiety was assessed with the Beck Anxiety Inventory, sensory processing with the Dunn Sensory Profile, and play with the Revised Knox Preschool Play Scale and Test of Playfulness. Results: Maternal anxiety was negatively correlated with play performance (ρ = −0.564, p < 0.001) and playfulness (ρ = −0.492, p < 0.001), and positively correlated with low registration and sensation-seeking raw scores (ρ = 0.474, p < 0.001 and ρ = 0.343, p = 0.008, respectively; higher raw scores indicate more typical, less atypical processing). Children with comorbid ADHD had mothers with higher anxiety and lower play scores. In a multivariable model (R² = 0.516), play performance (β = −0.411, p = 0.002) and, preliminarily, comorbid ADHD (β = 0.274, p = 0.027; only 10 children with ADHD) were independently associated with maternal anxiety; maternal education, employment, and school type were not. Conclusions: In young children with ASD, maternal anxiety symptoms were most strongly associated with the child’s play performance, while a preliminary association with co-occurring ADHD requires confirmation in larger samples; these findings support considering maternal wellbeing in family-centered occupational therapy assessment.

Background: Lateral epicondylitis (tennis elbow) is a common cause of lateral elbow pain and upper-extremity dysfunction. Mesotherapy, a minimally invasive local injection technique, has shown promising results in musculoskeletal pain, but comparative data versus saline injection in lateral epicondylitis remain scarce. This study compared clinical outcomes of mesotherapy and saline injection in patients with lateral epicondylitis. Methods: In this retrospective, non-randomized comparative study, medical records of 55 patients with lateral epicondylitis who received mesotherapy (n = 28) or saline injection (n = 27) in routine clinical practice were reviewed. Pain intensity (Visual Analog Scale, VAS), grip strength, pinch strength, and upper-extremity function (QuickDASH) were assessed at baseline and 15 days after the first treatment session, with comparisons adjusted for baseline values, age, sex, and symptom duration. Results: Both groups showed significant within-group improvement in VAS, pinch strength, and QuickDASH scores, while grip strength improved significantly only with mesotherapy. VAS reduction was significantly greater with mesotherapy (mean change 4.25 ± 2.08 vs. 2.48 ± 1.67; p = 0.001; Hedges’ g = 0.92), as was grip strength improvement (median change 4.00 vs. 1.00; p < 0.001; r = 0.48); both remained significant after adjustment (p < 0.001 and p = 0.001). No significant between-group differences emerged for pinch strength (p = 0.461) or QuickDASH (p = 0.893). Conclusions: Mesotherapy was associated with significantly greater short-term improvement in pain intensity and grip strength than saline injection in lateral epicondylitis, without a clear advantage in pinch strength or patient-reported function. Given the non-randomized design and short follow-up, these findings should be considered preliminary and require confirmation in prospective, randomized, saline-controlled trials with longer follow-up.