Mehmet Eflatun Deniz

Dr. Mehmet Eflatun Deniz


Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 June 2024 in International Urology and Nephrology
Verified
Journal Article
Closed access
PDF file
MKMehmet Vehbi Kayra
Mehmet Vehbi Kayra
MDMehmet Eflatun Deniz
Mehmet Eflatun Deniz
COCevahir Ozer
Cevahir Ozer
SGSezgin Guvel
Sezgin Guvel
SSSamet Senel
Samet Senel

1 January 2019 in Urology Research and Practice
Verified
Journal Article
Closed access
ZGZafer Gökhan Gürbüz
Zafer Gökhan Gürbüz
NŞNevzat Can Şener
Nevzat Can Şener
EVEdiz Vuruşkan
Ediz Vuruşkan
MDMehmet Eflatun Deniz
Mehmet Eflatun Deniz
GGGüçlü Gürlen
Güçlü Gürlen
FOFerhat Ortoğlu
Ferhat Ortoğlu
Objective: Kidney stones in renal pelvis may be treated using various methods. For larger stones, percutaneous nephrolitotomy (PNL) is the first choice of option; where for smaller stones, shock wave lithotripsy (SWL) or flexible ureteroscopy (F-URS) could be more suitable options. In this article we aimed to compare the outcomes of F-URS and SWL on the treatment of renal pelvis stones




10 April 2026 in Urolithiasis
Verified
Journal Article
Open access
PDF file
FÇFerhat Çoban
Ferhat Çoban
Hüseyin KUTLUHüseyin KUTLU
Hüseyin KUTLU
KAKağan Türker Akbaba
Kağan Türker Akbaba
MDMehmet Eflatun Deniz
Mehmet Eflatun Deniz
BKBedreddin Kalyenci
Bedreddin Kalyenci
Steinstrasse is an important complication following extracorporeal shock wave lithotripsy; however, predictive models for risk factors in pediatric populations remain limited. This study aimed to develop and externally validate an explainable machine learning model for predicting steinstrasse formation after ESWL in children. This two-center retrospective study included 807 pediatric patients (< 18 years) who underwent ESWL for renal stones (2015–2025). The internal cohort comprised 685 patients (Adıyaman), while the external validation cohort consisted of 122 patients (Adana). Twenty-six preoperative variables were evaluated. Optimal predictors were identified through consensus-based feature selection using eight algorithms. Thirteen machine learning algorithms were compared using nested cross-validation. Model interpretability was assessed through SHAP, LIME, and partial dependence analyses. The overall steinstrasse incidence was 10.5% (85/807). Nine predictors were selected: S.T.O.N.E. Score, Triple-D Score, age, stone perimeter, stone depth, Hounsfield unit, stone volume, distal ureteral diameter, and skin-to-stone distance. XGBoost demonstrated optimal external validation performance (AUC = 0.949, sensitivity = 90%, specificity = 99.1%, MCC = 0.891) and exhibited excellent generalizability (ΔAUC = 0.001). Explainable artificial intelligence analyses identified age (mean|SHAP|=1.965) and distal ureteral diameter (mean|SHAP|=1.575) as dominant predictors with significant interaction (SHAP = 0.458). Decision curve analysis confirmed clinical utility across a threshold range of 2%–98%. This externally validated model accurately predicts steinstrasse formation using routine preoperative parameters. Integration of patient age, ureteral anatomy, and stone characteristics may guide decisions between ESWL, prophylactic stenting, or alternative endoscopic approaches in pediatric patients.