Helge L. Waldum was born 110546. Head of Department of Gastroenterology and Hepatology, St. Olavs Hospital, Trondheim for 20 years. Professor I for 25 years at Department of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway. MD, University of Oslo, Norway, 11.21, result reported to the King. Specialist in Internal Medicine and Gastroenterology 1980. Thesis (PhD): “Studies on group I pepsinogens and secretin” University of Tromsø, 1980 Thesis, Docteur d‘Etat : « La cellule ECL, une cellule clé dans la muquese gastric » (Tres honorable avec felicitations), Paris 1993. Research within the areas of: gastric acid secretion, gastrointestinal hormones, gastric pathology , tumour classification, carcinogenesis, the role of neuroendocrine cells , differentiated cell contra stem cell origin of cancers (paradigm shift?), neuroendocrine markers (chromogranin A), problems related to gastric acid inhibition (gastric cancer and infections including by prions), nicotine toxicity, and carcinoid disease with valvular heart disease and the role of serotonin in cardiac valvular disease in general. Solved the interaction between gastric acid secretagogues and the localization of the gastrin receptor. Showed rebound acid hypersecretion after PPI. Described close relation between regulation of function and growth with implications for tumourigenesis and role of neuroendocrine cells. Found no toxicity of long-term inhaled nicotine in rats
The Royal Norwegian Order of Saint Olav, Knight of 1. class
The King of Norway
For the contribution in basic and clinical medicine (translational research)