Sergio Di Nitto

Dr. Sergio Di Nitto


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 August 2025 in Bioengineering
Verified
Journal Article
Open access
PDF file
Ludovica ApaLudovica Apa
Ludovica Apa
SNSergio Di Nitto
Sergio Di Nitto
MPMauro Palmieri
Mauro Palmieri
PFPietro Familiari
Pietro Familiari
Emanuele RizzutoEmanuele Rizzuto
Emanuele Rizzuto
ZPZaccaria Del Prete
Zaccaria Del Prete
The aim of this work is to analyse the effectiveness of the medical use of the Cavitron Ultrasonic Surgical Aspirator (CUSA) in microsurgical treatment of Intramedullary Spinal Cord Tumors (IMSCTs), with a focus on the thermo-mechanical effects on neighbouring tissues to assess any potential damage. Indeed, CUSA emerges as an innovative solution, minimally invasive tumor excision technique, enabling controlled and focused operations. This study employs a Finite Element Analysis (FEA) to simulate the vibratory and thermal interactions occurring during CUSA application. A computational model of a vertebral column segment affected by an IMSCT was developed and analysed using ANSYS 2024 software. The simulations examined strain distribution, heat generation, and temperature propagation within the biological tissues. The FEA results demonstrate that the vibratory-induced strain remains highly localised to the application site, and thermal effects, though measurable, do not exceed the critical safety threshold of 46 °C established in the literature. These findings suggest that CUSA can be safely used within defined operational parameters, provided that energy settings and exposure times are carefully managed to mitigate excessive thermal accumulation. These conclusions contribute to the understanding of the thermo-mechanical interactions in ultrasonic tumour resection and aim to assist medical professionals in optimising surgical protocols.

14 July 2026 in Bioengineering
Verified
Journal Article
Open access
PDF file
Ludovica ApaLudovica Apa
Ludovica Apa
SNSergio Di Nitto
Sergio Di Nitto
MPMauro Palmieri
Mauro Palmieri
PFPietro Familiari
Pietro Familiari
Emanuele RizzutoEmanuele Rizzuto
Emanuele Rizzuto
ZPZaccaria Del Prete
Zaccaria Del Prete
Sergio Di Nitto was not included as an author in the original publication