Background: Parenting stress is a known risk factor for children’s social anxiety, yet the mediating and moderating mechanisms underlying this relationship remain underexplored, particularly regarding gene–environment interactions. This quantitative, cross-sectional study, grounded in diathesis-stress and family process theories, examined whether maladaptive parenting mediates the link between parenting stress and children’s social anxiety, and whether FKBP5 gene variation moderates this mediation. Methods: A sample of 1774 fourth- to sixth-grade students (aged 10–14 years) and their parents participated. Parenting stress and maladaptive parenting were parent-reported, children’s social anxiety was self-reported, and children’s FKBP5-related cumulative genetic score was derived from four SNPs (rs4713916, rs1360780, rs3800373, rs9296158). Moderated mediation analyses were conducted. Results: Parenting stress was significantly and positively associated with children’s social anxiety. Maladaptive parenting partially mediated this relationship. The FKBP5 showed a marginally significant moderating effect, with simple slope analysis suggesting parenting stress was more strongly associated with child social anxiety among children with higher genetic risk. No moderating effect was found for the path from maladaptive parenting to social anxiety. Conclusions: Parenting stress is associated with children’s social anxiety both directly and indirectly through maladaptive parenting, with FKBP5-related cumulative genetic risk potentially moderating the direct effect. These findings offer preliminary evidence that may inform preventive interventions targeting parenting stress, although replication is needed.

This study examines the effectiveness of the University–Government–Kindergarten Collaboration (UGK) model in training early childhood teacher candidates (TCs), using the Education for Sustainable Development (ESD) framework to assess its role in enhancing TCs’ competencies. Data were collected through a survey of 210 TCs and in-depth interviews with 12 participants. The findings indicate a structural imbalance in UGK: while university–kindergarten collaboration shows some effectiveness, the lack of governmental leadership weakens tripartite synergy. From an ESD perspective, although UGK fosters basic collaborative skills, it does not systematically develop higher-order ESD competencies such as systems thinking, normative awareness, critical thinking, and strategic action. By shifting the focus from institutional to student experience, this study offers a new analytical framework for teacher education models. It concludes that optimizing UGK requires stronger governmental coordination, deeper university–kindergarten cooperation, and explicit integration of ESD core competencies throughout the training system.