Marc Bonnefoy

Prof. Marc Bonnefoy

Centre Hospitalier Lyon-Sud, Service de Gériatrie, Lyon, France

Research Focus & Metrics

Academic Career Length

32Years (1995-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2009 in The Journal of nutrition, health and aging
Verified
Journal Article
Open access
PDF file
GKGabor Abellan Van Kan
Gabor Abellan Van Kan
YRY. Rolland
Y. Rolland
SAS. Andrieu
S. Andrieu
JBJ. Bauer
J. Bauer
OBO. Beauchet
O. Beauchet
BVB. Vellas
B. Vellas
The use of a simple, safe, and easy to perform assessment tool, like gait speed, to evaluate vulnerability to adverse outcomes in community-dwelling older people is appealing, but its predictive capacity is still questioned. The present manuscript summarises the conclusions of an expert panel in the domain of physical performance measures and frailty in older people, who reviewed and discussed the existing literature in a 2-day meeting held in Toulouse, France on March 12–13, 2009. The aim of the IANA Task Force was to state if, in the light of actual scientific evidence, gait speed assessed at usual pace had the capacity to identify community-dwelling older people at risk of adverse outcomes, and if gait speed could be used as a single-item tool instead of more comprehensive but more time-consuming assessment instruments.

1 May 2017 in The Lancet Neurology
Verified
Journal Article
Closed access
SASandrine Andrieu
Sandrine Andrieu
SGSophie Guyonnet
Sophie Guyonnet
NCNicola Coley
Nicola Coley
CCChristelle Cantet
Christelle Cantet
MBMarc Bonnefoy
Marc Bonnefoy
POPascale Olivier-Abbal
Pascale Olivier-Abbal

1 December 2017 in Clinical Nutrition
Verified
Journal Article
Closed access
PCPhilippe Caillet
Philippe Caillet
ELEvelyne Liuu
Evelyne Liuu
ARAgathe Raynaud-Simaon
Agathe Raynaud-Simaon
MBMarc Bonnefoy
Marc Bonnefoy
OGOlivier Guerin
Olivier Guerin
Éléna PaillaudÉléna Paillaud
Éléna Paillaud

1 January 2001 in Journal of the American Geriatrics Society
Verified
Journal Article
Closed access
PDF file
MBMarc Bonnefoy
Marc Bonnefoy
SNSylvie Normand
Sylvie Normand
CPChristiane Pachiaudi
Christiane Pachiaudi
JLJean Renã© Lacour
Jean Renã© Lacour
MLMartine Laville
Martine Laville
TKTomasz Kostka
Tomasz Kostka

1 March 2015 in The Journal of nutrition, health and aging
Verified
Journal Article
Open access
PDF file
MBMarc Bonnefoy
Marc Bonnefoy
GBG. Berrut
G. Berrut
BLB. Lesourd
B. Lesourd
MFM. Ferry
M. Ferry
TGThomas Gilbert
Thomas Gilbert
YRY. Rolland
Y. Rolland
Frailty is a geriatric syndrome that predicts disability, morbidity and mortality in the elderly. Poor nutritional status is one of the main risk factors for frailty. Macronutrients and micronutrients deficiencies are associated with frailty. Recent studies suggest that improving nutritional status for macronutrients and micronutrients may reduce the risk of frailty. Specific diets such as the Mediterranean diet rich in anti-oxidants, is currently investigated in the prevention of frailty. The aim of this paper is to summarize the current body of knowledge on the relations between nutrition and frailty, and provide recommendations for future nutritional research on the field of frailty.

1 May 2003 in British Journal of Nutrition
Verified
Journal Article
Open access
PDF file
MBMarc Bonnefoy
Marc Bonnefoy
CCC. Cornu
C. Cornu
SNS. Normand
S. Normand
FBF. Boutitie
F. Boutitie
FBF. Bugnard
F. Bugnard
MLM. Laville
M. Laville
Fighting against inactivity and inadequate nutritional intake are of utmost importance in the elderly. To our knowledge, the few studies which have been performed were conducted for only a short period and the results do not permit formal conclusions to be drawn. We therefore tried to fill this gap in our knowledge by determining whether an intervention combining an acceptable progressive exercise programme and nutritional supplements would be feasible for a long-term period in the very frail elderly, and would bring about concomitant benefits in body composition and muscle power. Accordingly, this exercise and nutritional combination was assessed in the frail elderly in a 9-month randomised trial with a factorial design. Fifty-seven elderly volunteers over 72 years, from sixteen retirement homes in Lyon, France participated in the study. Dietary supplements were compared with placebo, and physical exercise was compared with memory training. Main outcome measures were fat-free mass (FFM) and muscle power. FFM was determined by labelled water, and muscle power was measured by a leg-extensor machine. At 9 months, the compliance was 63 % for exercise sessions, and 54 % for nutritional supplements. In patients with dietary supplements, muscle power increased by 57 % at 3 months (P=0·03), and showed only a tendency at 9 months; although FFM increased by 2·7 % at 9 months, the difference was not significant (P=0·10). Exercise did not improve muscle power at 9 months, but improved functional tests (five-time-chair rise,P=0·01). BMI increased with supplements (+3·65 %), but decreased with placebo (−0·5 %) at 9 months (P=0·007). A long-term combined intervention is feasible in frail elderly individuals with a good rate of compliance. Nutritional supplements and exercise may improve muscle function. Despite no significant results on FFM, due to the limited number of volunteers, combined intervention should be suggested to counteract muscle weakness in the frail elderly.