Hiroshi Sakagami

Prof. Dr. Hiroshi Sakagami

Meikai University Research Institute of Odontology (M-RIO)
orcid

Research Focus & Metrics

Academic Career Length

47Years (1980-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 February 2008 in Autophagy
Verified
Journal Article
Closed access
DKDaniel J. Klionsky
Daniel J. Klionsky
HAHagai Abeliovich
Hagai Abeliovich
PAPatrizia Agostinis
Patrizia Agostinis
DADevendra K Agrawal
Devendra K Agrawal
GAGjumrakch Aliev
Gjumrakch Aliev
RDRussell L Deter
Russell L Deter
(2008). Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy: Vol. 4, No. 2, pp. 151-175.

1 August 1981 in Proceedings of the National Academy of Sciences
Verified
Journal Article
Closed access
PDF file
EAE Abe
E Abe
CMC Miyaura
C Miyaura
Hiroshi SakagamiHiroshi Sakagami
Hiroshi Sakagami
MTM Takeda
M Takeda
KKK Konno
K Konno
TST Suda
T Suda
Mouse myeloid leukemia cells can be induced to differentiate into macrophages in vitro by 1 alpha,25-dihydroxyvitamin D3, the active form of vitamin D3. The minimal concentration of 1 alpha,25-dihydroxyvitamin D3 to induce the cell differentiation was 0.12 nM. The degree of cell differentiation in various markers induced by 12 nM 1 alpha,25-dihydroxyvitamin D3 was nearly equivalent to that induced by 1 microM dexamethasone, the most potent known stimulator. Among several markers of the differentiation by 1 alpha,25-dihydroxyvitamin D3, phagocytic activity was induced within 24 hr, and this was followed by induction of lysozyme and locomotive activities. Similar changes were also induced by 0.01-1 microM 1 alpha-hydroxyvitamin D3. 25-Hydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 showed only weak inducing activity. These results suggest the possibility that, in addition to its wellknown biological activities in enhancing intestinal calcium transport and bone mineral mobilization, 1 alpha, 25-dihydroxyvitamin D3 is involved in the differentiation of bone marrow cells.

1 February 2002 in Phytochemistry
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Journal Article
Closed access
STShoko Taniguchi
Shoko Taniguchi
YIYoko Imayoshi
Yoko Imayoshi
EKEri Kobayashi
Eri Kobayashi
YTYoshie Takamatsu
Yoshie Takamatsu
HIHideyuki Ito
Hideyuki Ito
TYTakashi Yoshida
Takashi Yoshida

1 August 2002 in Toxicology
Verified
Journal Article
Closed access
SFSeiichiro Fujisawa
Seiichiro Fujisawa
TAToshiko Atsumi
Toshiko Atsumi
YKYoshinori Kadoma
Yoshinori Kadoma
Hiroshi SakagamiHiroshi Sakagami
Hiroshi Sakagami

1 April 2002 in Bioorganic & Medicinal Chemistry
Verified
Journal Article
Closed access
MKMasami Kawase
Masami Kawase
ASAnamik Shah
Anamik Shah
HGHarsukh Gaveriya
Harsukh Gaveriya
NMNoboru Motohashi
Noboru Motohashi
Hiroshi SakagamiHiroshi Sakagami
Hiroshi Sakagami
JMJoseph Molnár
Joseph Molnár

1 June 2015 in Journal of Applied Oral Science
Verified
Journal Article
Open access
PDF file
Rene Garcia-ContrerasRene Garcia-Contreras
Rene Garcia-Contreras
RSRogelio J Scougall-Vilchis
Rogelio J Scougall-Vilchis
RCRosalia Contreras-Bulnes
Rosalia Contreras-Bulnes
Hiroshi SakagamiHiroshi Sakagami
Hiroshi Sakagami
RMRaul Alberto Morales-Luckie
Raul Alberto Morales-Luckie
HNHiroshi Nakajima
Hiroshi Nakajima
The use of nanoparticles (NPs) has become a significant area of research in Dentistry.