Depressive disorders are among the most disabling diseases experienced around the world, and their incidence has significantly increased over the last few decades due to multiple environmental, social, and biological factors. The search for new pharmacological alternatives to treat depression is a global priority. In preclinical research, molecules obtained from plants, such as flavonoids, have shown promising antidepressant-like properties through several mechanisms of action that have not been fully elucidated, including crossing of the blood brain barrier (BBB). This review will focus on discussing the main findings related to the participation of the serotonergic system and brain-derived neurotrophic factor (BDNF) on the antidepressant-like effect of some flavonoids reported by behavioral, neurochemical, and molecular studies. In this sense, evidence shows that depressive individuals have low levels of serotonin and BDNF, while flavonoids can reverse it. Finally, the elucidation of the mechanism used by flavonoids to modulate serotonin and BDNF will contribute to our understanding of the neurobiological bases underlying the antidepressant-like effects produced by these natural compounds.

Public health in Mexico was on alert since the World Health Organization declared a pandemic of COVID-19. This disease represents a challenge not only for the health system but also for the education system, which implement emerging measures such as online education. In Mexico online education has several limitations associated with computer and internet access, which affect the academic achievement of the students. Additionally, the main measures against the pandemic are social isolation, but this measure can generate stress and affect the academic achievement and mental health of the population. The present review was based on Mexican scientific and journalistic sources, and a thesaurus system such as Medical Subject Headings (MeSH) terms to find original articles to social isolation, mental health, and academic achievement. The contribution of this chapter is to describe the effects that social isolation has caused on mental health and scholar challenges in the Mexican student population.

El estudio tuvo como objetivo determinar la frecuencia de sobrepeso y obesidad en indígenas nahuas de Ixtaczoquitlán, Veracruz, México. Para ello, se realizó un estudio transversal entre los años 2010-2011; donde se calculó el índice de masa corporal (IMC). Para la definición de sobrepeso y obesidad se emplearon las categorías de la Organización Mundial de la Salud (OMS) y los de la Norma Oficial Mexicana (NOM). Se incluyó 227 nahuas (77,5% mujeres). Según los lineamientos de la OMS, la proporción de nahuas con sobrepeso fue de 41%, y de obesidad 36,5%; y según la NOM fue de 11,4 y 69,2% respectivamente. En conclusión, la frecuencia de sobrepeso y obesidad en indígenas nahuas es alta. Deben realizarse estudios enfocados a determinar la prevalencia y factores de riesgo y, con ello, desarrollar estrategias de prevención que mejoren la calidad de salud de estas poblaciones.

Las redes sociales influyen en la compra de productos o uso de servicios en la población, tal es el caso en los temas de salud por lo que, la Comisión Federal para la Protección contra Riesgos Sanitarios (COFEPRIS) lanzó la Grrupi, una guía para publicidad responsable, evitando la difusión de información engañosa, por lo que esta publicidad debe ser analizada por la Secretaria de Salud, para ser una herramienta para realizar una difusión sanitaria adecuada y con ello cumplir con el Reglamento de la Ley General de Salud en Materia de Publicidad.