Sirisha Kaniganti

Dr. Sirisha Kaniganti

orcid

Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 February 2026 in Plant-Environment Interactions
Verified
Journal Article
Open access
SKSirisha Kaniganti
Sirisha Kaniganti
HSHIMANSHU SAINI
HIMANSHU SAINI
ACA. K. Chaitanya
A. K. Chaitanya
NHNiranjan Hegde
Niranjan Hegde
PSPriya Shah
Priya Shah
HJHarsha Rayudu Jamedar
Harsha Rayudu Jamedar
CRISPR/Cas‐based genome editing has emerged as a transformative tool for precise genetic improvement of cereal crops. Recent advances in CRISPR technologies, including Cas9, Cas12, Cas13, base editing, and prime editing, have enabled targeted modification of genes and regulatory elements controlling yield, stress tolerance, and grain nutritional quality in major cereals such as rice, wheat, maize, and barley. This review summarizes current progress in CRISPR‐mediated genome editing systems, delivery strategies, and representative applications in cereal crop improvement. Emphasis is placed on how genome editing reprograms enzymatic activities and biological pathways underlying complex agronomic traits rather than acting through single‐gene effects. The review also discusses challenges related to trait complexity, regulatory considerations, and prospects for translating genome‐edited cereal crops from laboratory research to field‐level application. Collectively, this review highlights the potential of CRISPR/Cas genome editing as a powerful approach for developing high‐yielding, resilient, and nutritionally improved cereal crops.