Hao Guo

Dr. Hao Guo

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 October 2025 in Materials Science and Engineering: C
Verified
Journal Article
Closed access
YLYijun Liu
Yijun Liu
GJGuohua Jiang
Guohua Jiang
BGBin Gao
Bin Gao
TZTianjing Zhao
Tianjing Zhao
LLLong Li
Long Li
CZCan jun Zeng
Can jun Zeng

23 December 2022 in Foot & Ankle International
Verified
Journal Article
Closed access
NSNian Sun
Nian Sun
JCJunjian Chen
Junjian Chen
ZCZhuhong Chen
Zhuhong Chen
CZCan jun Zeng
Can jun Zeng
HGHao Guo
Hao Guo
Background: Few studies have reported the clinical outcomes of fusion surgeries for type II accessory naviculars. Whether the combination of accessory naviculars and asymptomatic flatfoot will result in worse outcomes in accessory navicular surgeries remains to be elucidated. Our study aims to report the clinical outcomes of fusion for type II accessory naviculars and make a subgroup comparison among accessory navicular patients with or without asymptomatic flatfeet. Methods: From May 2017 to June 2021, all painful type II accessory naviculars with or without asymptomatic flatfeet in our inpatient center were reviewed, and those who only underwent fusion surgeries were included in the retrospective study. Visual analog scale (VAS) scores, American Orthopaedic Foot & Ankle Society (AOFAS) midfoot scores, Tegner activity level scores, complications, patient-reported satisfaction, and imaging results (Meary angle in the weightbearing lateral view, talo–first metatarsal angle and talonavicular coverage angle in the weightbearing anteroposterior view) were used to describe outcomes. Results: Thirty-two eligible patients responded to the latest follow-up request and were included in this study. The mean follow-up duration was 37.1 ± 16.0 months. The average VAS pain score improved from 4.7 ± 1.8 preoperatively to 0.9 ± 1.2 at the latest follow-up ( P<.001). The average AOFAS midfoot score improved from 67.1 ± 8.5 preoperatively to 90.2 ± 10.7 at the latest follow-up ( P<.001). The preoperative and postoperative Tegner activity level scores were similar (3.3 ± 1.5 vs 3.5 ± 1.6, P=.136). The overall complication rate was 37.5%. The most common complication was nonunion (31.3%). The overall satisfaction rate was 90.6%. Similar outcomes were observed between the flatfoot and the nonflatfoot subgroups. Conclusion: Fusion for painful type II accessory naviculars resulted in good symptom relief, function improvement, and patient satisfaction at midterm follow-up, but the nonunion rate was relatively high. Fusion for painful type II accessory naviculars with or without asymptomatic mild to moderate flatfoot brought about similar clinical outcomes. Level of Evidence: Level III, retrospective comparative study.

6 March 2024 in Foot & Ankle International
Verified
Journal Article
Closed access
HGHao Guo
Hao Guo
HYHaohan Yan
Haohan Yan
HYHan Yan
Han Yan
YLYijun Liu
Yijun Liu
CZCan jun Zeng
Can jun Zeng
Background: Whether arthroscopic microfracture is effective in treating cystic osteochondral lesions of the talus (OLTs) remains controversial. In this study, outcome parameters in patients with small and shallow subchondral cysts are compared to patients without cysts with the hypothesis that equivalent outcomes may be found after primary microfracture treatment. Methods: From 2018 to 2021, all 50 OLTs treated with arthroscopic microfracture in the authors’ hospital were retrospectively reviewed for eligibility. Single unilateral symptomatic lesions were included and divided into the cyst and noncyst groups, whereas kissing lesions and arthritic lesions were excluded. Numeric rating scale (NRS) scores, American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot scores, Tegner activity level scores, Foot and Ankle Ability Measure (FAAM) scores, and magnetic resonance (MR) imaging results were used to describe outcomes. Results: A total of 35 patients were included, 16 in the cyst group and 19 in the noncyst group. The patient characteristics were similar between the 2 groups ( P > .05). In the cyst group the average cysts depth was 5.0 ± 1.3 mm. After a mean follow-up duration of 36.2 ± 10.2 months, no significant differences were found between the 2 groups in NRS, AOFAS, FAAM, or Tegner score improvement ( P > .05). Three patients (19%) in the cyst group had no NRS score improvement. Conclusion: OLTs with small and shallow subchondral cysts can be treated with arthroscopic microfracture and achieve similar outcomes as noncystic lesions. A few cystic lesions may not respond to microfracture treatment. Level of Evidence: Level III, retrospective comparative study.

30 July 2024 in Foot & Ankle International
Verified
Journal Article
Closed access
HGHao Guo
Hao Guo
NSNian Sun
Nian Sun
QZQi Zhou
Qi Zhou
ZCZhuhong Chen
Zhuhong Chen
YLYijun Liu
Yijun Liu
CZCan jun Zeng
Can jun Zeng
Background: Two types of suture anchor insertion pathways (anterolateral portal vs lateral accessory portal) are used in arthroscopic anterior talofibular ligament (ATFL) repair. However, it is not clear which one is the better choice. This study aims to compare the clinical outcomes of these 2 suture anchor insertion pathways when performing arthroscopic ATFL lasso-loop repair for the treatment of chronic lateral ankle instability (CLAI). Methods: From 2019 to 2021, patients with CLAI who underwent arthroscopic ATFL lasso-loop repair were retrospectively reviewed and divided into the anterolateral portal (ALP) group and the lateral accessory portal (LAP) group. A 1:1 propensity score matching was used to control confounding factors based on age, sex, body mass index, follow-up duration, preoperative visual analog scale (VAS) score, and Tegner score (ALP group, n = 26; LAP group, n = 26). Karlsson score, VAS score, Tegner score, operation time, anterior drawer test results, patient symptoms, and magnetic resonance (MR) evaluation of ATFL quality were used to describe the outcomes. Results: The patient characteristics and follow-up durations were similar between the 2 groups. After a mean follow-up duration of 28.8 ± 2.3 months, the ALP group had significantly better Karlsson score, VAS score, and Tegner score improvement than the LAP group, with fewer symptoms. Seven patients in the LAP group still had a feeling of ankle instability, and 3 of them exhibited ankle laxity. Conclusion: In this study, we found that inserting the suture anchor through the anterolateral portal was associated with better outcomes compared to that through the lateral accessory portal when performing arthroscopic ATFL lasso-loop repair for CLAI patients. The improvement was greater for pain relief and function and was associated with a lower frequency of subjective ankle instability.

15 October 2025 in Foot & Ankle International
Verified
Journal Article
Closed access
CZCan jun Zeng
Can jun Zeng
NSNian Sun
Nian Sun
YWYuxuan Wei
Yuxuan Wei
FJFeijuan Jiang
Feijuan Jiang
YLYijun Liu
Yijun Liu
HGHao Guo
Hao Guo
Background: This study aimed to evaluate the efficacy and safety of an accelerated postoperative rehabilitation protocol (APRP), which emphasizes immediate full weightbearing (FWB), muscle strength and balance training as early as possible, after arthroscopic anterior talofibular ligament (ATFL) repair for chronic lateral ankle instability (CLAI). Methods: Patients with CLAI who underwent modified ATFL lasso-loop repair procedures between December 2019 and November 2022 were retrospectively screened. Based on their postoperative rehabilitation protocols, subjects were divided into the APRP group and the conventional postoperative rehabilitation protocol (CPRP) group using 1:2 propensity score matching. Clinical outcome measures comprised the Karlsson score, visual analog scale (VAS) for pain, Tegner score, anterior drawer test findings, complications, and magnetic resonance imaging–based ATFL Quality Score (ATFLQS). A receiver operating characteristic curve analysis was employed to investigate the association between preoperative ATFLQS and clinical outcomes in the APRP group. Results: The APRP group demonstrated comparable improvements in Karlsson score (31.8 ± 17.6 vs 36.0 ± 13.4, P = .267) and Tegner score (2 [−1 to 6] vs 2 [0 to 5], P = .168) to the CPRP group. Although the APRP group showed statistically superior VAS pain score improvement (3.5 ± 2.3 vs 2.2 ± 0.7, P < .001), the clinical significance of this 1.3-point difference remains uncertain given the lack of validated minimal clinically important difference thresholds for VAS pain in ankle ligament surgery populations. The overall complication rates between the 2 groups showed no statistically significant difference (10/54 vs 7/28, P = .492). Comparable ATFL quality was also found between the 2 groups based on the ATFLQS. The optimal ATFLQS threshold value for predicting functional outcomes was determined to be 2.5, based on the maximal Youden index, demonstrating a sensitivity of 82.4% and specificity of 83.3%. Conclusion: Comparable outcomes between the 2 groups were found following arthroscopic ATFL repair for CLAI, with no recurrence observed. FWB, muscle strength, and balance training as early as possible demonstrates both efficacy and safety after surgery. However, patients with preoperative ATFLQS <2.5 receiving APRP may have a significantly increased risk for suboptimal functional recovery.

28 August 2024 in Chinese Journal of Traumatology
Verified
Journal Article
Open access
YWYuxuan Wei
Yuxuan Wei
ZCZhuhong Chen
Zhuhong Chen
NSNian Sun
Nian Sun
ZTZhu Tang
Zhu Tang
HGHao Guo
Hao Guo
CZCan jun Zeng
Can jun Zeng
Autologous osteoperiosteal transplantation (AOPT) is one of the most feasible and effective techniques for cystic osteochondral lesions of the talus (OLT). However, few reports have been reported about the process of graft-host bone healing and bone articular surface reconstruction, which help us to further understand the actual situation of bone healing and modify surgical methods. The case series study retrospectively evaluated 33 osteochondral lesions in 30 patients undertaking AOPT for OLT with subchondral cysts from December 2016 to October 2021. According to CT observation, we used 4 variables to describe the bony articular repair, including the integration of the articular surface, the height of the bone filling, the status of bone union, and the appearance of bone resorption or cystic change. We also analyzed the demographic data and clinical function. Descriptive statistics were used for demographic and clinical variables. Normally distributed data were presented as mean ± SD, and non-normally distributed data were presented as median (Q1, Q3). Associations between these variables and the primary clinical outcomes were examined using t-test or one-way ANOVA test for continuous variables. The patients' mean age was (41.7 ± 14.0) years old and the mean follow-up time was (29.6 ± 17.8) months. The chondral lesion size was (14.3 ± 4.1) mm. The cyst depth was (10.9 ± 3.7) mm. Significant improvements were observed in functional outcomes (according to the numeric rating scale for pain when walking and the American orthopedic foot and ankle society score) between the preoperative and latest follow-up evaluations, from 4.2 ± 2.1 to 2.2 ± 2.0 (p < 0.001), and from 66.8 ± 12.9 to 83.2 ± 10.4, respectively (p < 0.001). The overall satisfaction reached 8.3 of 10 points. All patients returned to sports and their median daily steps reached 8000 steps with 27 (81.8%) patients walking over 6000 steps daily. According to CT observation, "discontinuous bony articular surface and gap > 1 mm" was found in 27 grafts (81.8%), and "below the level of the adjacent articular surface, ≤ 1 mm" in a third of the grafts. Abnormal height of bone filling affected numeric rating scale score (p = 0.049) and American Orthopedic Foot and Ankle Society score (p = 0.027). Of note, bone resorption or cystic changes appeared in up to 13 autografts (39.4%). AOPT is an effective and acceptable technique for cystic OLT. Bone reconstruction is essential for large cystic OLT. How to get better bony articular reconstruction and avoid cyst recurrence should still be paid more attention.