Vibriosis, caused by various Vibrio species, poses a significant challenge in the aquaculture of Litopenaeus vannamei. Bacteriophages present a promising biocontrol option due to their ability to specifically target and kill bacteria without harmful side effects. This study evaluates the effectiveness of bacteriophages isolated from shrimp intestines and mangrove sediment in controlling Vibrio infections in L. vannamei. Using a Completely Randomized Design (CRD) with five treatment groups and four replications, including control, pathogen-exposed, and various phage treatments, the research found that purified bacteriophages, especially those from shrimp intestines (26 × 10⁹ PFU/mL), significantly inhibited bacterial growth in vitro. In vivo, phage-treated shrimp showed improved immune responses and higher survival rates than controls. Although total hemocyte counts remained unchanged, increased phagocytic activity suggests that phage therapy could be an effective and sustainable method for managing Vibrio infections in shrimp farming.

The goal of this study was to investigate the yellowfin tuna marketing chain in PPP Pondok Dadap Sendang Biru. Additionally, this study determined the margin and price share earned by yellowfin tuna fisherman. This research employed a survey strategy that included direct observation and interviews. The data used were original sources collected during October and November 2021. The respondents were chosen using the snowball sampling technique, which is a technique for identifying informants or respondents who possess a wealth of information on the research being conducted. There were 37 respondents. According to the study's findings, there are three distinct channels for yellowfin tuna marketing at PPP Pondok Dadap Sendang Biru. In chain 2, retailers earned the largest overall margin of Rp. 8,864/Kg, or 29 percent. In channel 3, retailers earned the largest overall margin of Rp. 12,000/Kg, or 34%. The biggest Fisherman's share, at 62 percent, is in the type 2 marketing chain.Keywords: fishermans share; marketing chain; margin; tuna

Fisheries and Aquatic Sciences

This study explores the antihyperglycemic and antihypercholesterolemic potential of Skeletonema costatum, a marine microalga, in diabetic and hypercholesterolemic mice models. The study compared the effects of S. costatum in infusion (SCI) and powder (SCP) forms at two concentrations (2.5% and 5%) with standard treatments, including glibenclamide for diabetes and simvastatin for hypercholesterolemia, as well as a no-treatment control. Over 21 days, SCP demonstrated significant and sustained reductions in both blood glucose and cholesterol levels, with the 2.5% SCP dose outperforming the 5% dose. SCI showed transient effects, with initial reductions in glucose and cholesterol levels followed by rebounds, likely due to the rapid metabolism of bioactive compounds. The powdered form's superior efficacy is attributed to its slower digestion and gradual release of omega-3 fatty acids, polyphenols, and bioactive peptides, which improve insulin sensitivity, reduce oxidative stress, and regulate lipid metabolism. Simvastatin showed the most pronounced cholesterol-lowering effect, confirming its efficacy as a standard therapy. The study underscores the potential of S. costatum, particularly SCP, as a natural alternative or complementary therapy for managing diabetes and hypercholesterolemia. Future investigations should optimize dosing, explore its synergistic effects with conventional treatments, and evaluate its long-term safety and therapeutic potential in humans.