Francesco Mallamace graduated in Physics in 1973. In 1974, he became a research and teaching assistant at Purdue University (USA). In 1976, he obtained a professorship in charge of Optics at the University of Messina; in 1981 he became associate professor in Structure of the Matter and in 1986 in General Physics. From 2000 onwards he has been a Full Professor of General Physics. Francesco Mallamace’s scientific activity, as testified by over 220 publications in international journals (with several published in journals of absolute excellence, e.g., Science, Natures, PNAS), focused mainly on the experimental study of Physics of Complex Systems and on radiation–matter interactions. He has given fundamental contributions to the study of these systems in non-equilibrium conditions and in non-ergodic transitions (gels, colloids, microemulsions, glasses, polymers, supercooled water, etc.). Furthermore, he developed new experimental techniques in the study of the radiation–matter interactions; especially by using high-intensity neutrons generated in nuclear reactors. In particular, one of the most used models is the “cap-and-gown" model (1995). By means of these techniques and by Nuclear Magnetic Resonance (NMR), he has studied, obtaining significant results, physical systems in non-linear thermal conditions.