Hypertension is becoming increasingly prevalent among the elderly. Family caregivers play an important role in caring for elderly people and empowering them to care for themselves. This study’s goal was to see how social support training for family caregivers affected changes in hypertension, total cholesterol, and high-density lipoprotein (HDL), and how such support led to the prevention of hypertension behaviors among the elderly in rural areas. This was a quasi-experimental study with 268 elderly people at risk of hypertension and their caregivers. Sixty seven pairs of elderly people and their caregivers were assigned to the intervention and control groups. Baseline data were collected in November 2020. The intervention group received the Social Support Family Caregiver Training Program (SSFCTP), while the control group received a regular program from the local health authority. The activity lasted 12 weeks, with home visits and telephone check-ups along the way, and data collection took place after the program ended. The final data were collected three months after the end of the intervention. An analysis of repeated measures ANOVA showed the overall effect of the SSFCTP on knowledge, self-efficacy, health care behaviors, and blood pressure among elderly people during three different time periods (p<0.05). Furthermore, the intervention program had a time-dependent effect on knowledge, blood pressure, and total cholesterol levels (p<0.05). In terms of caregiver outcomes, there was an overall difference among the degrees of knowledge, self-efficacy, and behaviors toward health care displayed by elderly hypertensive patients during the three different time periods (p<0.05). The average knowledge and self-efficacy of the participants improved after the intervention. As a result, better self-care behaviors and lower blood pressure and total cholesterol levels were observed among the elderly participants after the intervention. The programs emphasized the importance of caregivers’ roles in providing social support, boosting confidence, and encouraging participation in caring, monitoring, and assisting the elderly in controlling blood pressure and other health issues.

(1) Background: the 2019 coronavirus disease outbreak (COVID-19) has posed a major threat to public health and had a significant impact on all areas of people’s lives. Vaccines against COVID-19 have been developed to control the disease, and an array of personal hygiene measures has been introduced. As a result, information that will support and promote vaccination among populations as well as other health measures against COVID-19 are urgently needed. The goal of this research was to look into the knowledge about COVID-19 and how it relates to preventive behaviors and vaccination among people living in rural areas of northern Thailand. (2) Methods: a cross-sectional study was performed in four upper northern provinces of Thailand. A total of 1524 participants were recruited using the probability sampling technique. Questionnaires were distributed to collect data on general health information, as well as knowledge and preventive behaviors regarding COVID-19. (3) Results: more than half (55.9%) of the participants were female and had not received the COVID-19 vaccine (67.2%). Their mean age was 44.13 years. The majority had moderate COVID-19 knowledge and engaged in preventive behaviors (65.5% and 42.0%, respectively). A linear regression model showed that the COVID-19 knowledge score was related to the COVID-19 preventive behaviors score, with a standardized coefficient of 0.510, after adjusting for age, underlying disease, and body mass index (B = 2.64; 95%CI = 2.42, 2.87). Binary logistic regression revealed that after controlling for age, education, occupation, financial status, and current disease (AOR = 1.87; 95%CI = 1.64–2.13), the score of COVID-19 knowledge was significantly associated with having the COVID-19 vaccine. (4) Discussion: knowledge of COVID-19 is very important for people in rural regions to engage in COVID-19 prevention behaviors and vaccination. Relevant government agencies and health network partners should support proactive education campaigns emphasizing the risk of contracting the disease and its severity in order to promote vaccination against COVID-19 among unvaccinated groups. These campaigns can highlight COVID-19’s positive benefit-risk balance in the short and long term and ensure public safety measures against COVID-19.

Musculoskeletal disorders (MSDs) are one of the leading causes of occupational injuries and disabilities. The purpose of this study was to assess the prevalence of MSDs and occupational factors affecting MSDs among ethnic lychee–longan harvesting workers in northern Thailand. A cross-sectional study was conducted in the areas of three upper northern provinces of Thailand. The study areas are located in the highlands and rural plains, where many ethnic minority groups live, including Indigenous, Mien, Karen, and Lua. The majority of them work in a farm of perennial fruit trees, mainly lychee and longan. During the harvest season, 404 participants were recruited for the study using the convenience sampling technique. Data were collected using questionnaires that included general information, an ergonomic risk assessment, and a standardized Nordic questionnaire for assessing MSDs in 10 body parts. The average age of lychee–longan harvesting workers was 48.8 years. Almost all (99.5%) reported MSDs in one or more body regions in the previous seven days of work. The prevalence of MSDs was highest in the hands (82.9%), followed by the shoulders (82.2%) and the neck (79.7%). The total ergonomic risk scores, which included awkward posture, heavy carrying and lifting, repetitive activity, land slope, and equipment, were found to be significantly associated with MSDs in part of the neck (AOR = 1.17, 95%CI = 1.11–1.23), shoulder (AOR = 1.15, 95%CI = 1.10–1.21), elbow (AOR = 1.18, 95%CI = 1.12–1.24), hand (AOR = 1.12, 95%CI = 1.07–1.18), finger (AOR = 1.33, 95%CI = 1.24–1.44), upper back (AOR = 1.14, 95%CI = 1.09–1.20), lower back (AOR = 1.16, 95%CI = 1.11–1.22), hip (AOR = 1.11, 95%CI = 1.06–1.15), knee (AOR = 1.18, 95%CI = 1.12–1.24), and feet (AOR = 1.21, 95%CI = 1.15–1.28) when adjusting for ethnicity, sex, age, BMI, and work experience. Many parts of ethnic workers’ bodies have been affected by occupational injuries, with a high risk of upper extremity injury. As a result, using an ergonomic approach to improving the working environment and appropriate posture movement is very beneficial in preventing MSDs among ethnic harvesting workers.

Background: Herbal use is a conventional wisdom of health care that falls under complementary alternative medicine. The purpose of this research was to study factors affecting herbal-use behavior and glycated hemoglobin (HbA1c) levels in ethnic minorities living in the northern border of Thailand. Methods: A cross-sectional study was conducted in the three northern border provinces located in the highlands and rural plains between May–July 2022 among ethnic groups, including Hmong, Karen, Lua, and Indigenous. A total of 413 people were recruited for the study using a convenient sampling method. The data were obtained from face-to-face interviews using questionnaires and from blood samples. Results: The mean age of the participant was 50.2 years. More than half of the participants had abnormal HbA1c (> 6.5) (55.7%). The mean score for herbal-use behavior was 19.2 (SD = 3.77). An analysis of Pearson’s correlation coefficient found that herbal-use behavior was positively correlated with health literacy (r = 0.918). HbA1c was negatively correlated with health literacy and health behavior (r = -0.628, r = -0.557). Factors including age and people with diabetes were statistically significantly associated with herbal-use behavior, accounting for 42.3% of the variance. When adjusted for factors, health literacy was found to be statistically significantly associated with herbal-use behavior, which affected HbA1c levels. Conclusion: Health education programs among ethnic minorities should be focused on increasing health knowledge of the types and properties of herbs and herbal-use behavior to help lower blood sugar levels and understand the health effects and consequences of herbal-use.

Zanthoxylum rhetsa (Roxb.) DC. (Ma-Khwaen) is an economically important medicinal plant traditionally used for pain and inflammatory disorders. This study explored its phytochemical composition, biological activities, and potential for nano-spray product development. Methods: Ethanolic fruit extracts collected from five provinces in Northern Thailand were evaluated for extraction yield, total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity, and anti-inflammatory activity. Extracts from Nan Province were further selected for DPPH radical scavenging, GC–MS characterization, nitric oxide (NO) inhibition assay in LPS stimulated RAW 264.7 macrophages, nano-spray formulation development, and stability assessment. Results: Considerable phytochemical variation was observed among geographical origins, with TPC and TFC ranging from 19.47 to 103.09 mg GAE/g extract and 28.57 to 400.72 mg QE/g extract, respectively. The Nan whole-fruit extract exhibited the highest extraction yield (20.81%), whereas the pericarp extract showed the strongest antioxidant activity (IC₅₀ = 111.78 μg/mL). GC–MS analysis revealed anti-inflammatory phytochemicals, predominantly α-terpineol, geranyl acetate, n-hexadecanoic acid, oleic acid, and linalool. The selected extract demonstrated potent anti-inflammatory activity (IC₅₀ = 6.95 ± 0.44 μg/mL), exceeding that of prednisolone, and was successfully incorporated into a physically stable nano-spray formulation with 60-day storage stability. Conclusions: These findings provide scientific validation for the traditional use of Ma-Khwaen and support its development as a stable nano-spray formulation for muscle pain relief and inflammation alleviation.