Gamze AKBULUT

Dr. Gamze AKBULUT


Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2011 in Experimental and Therapeutic Medicine
Verified
Journal Article
Open access
PDF file
GAGamze AKBULUT
Gamze AKBULUT
Cancer and its treatment result in severe biochemical and physiological alterations associated with a deterioration of quality of life (QoL). Cancer-related malnutrition may evolve into cancer cachexia due to complex interactions between pro-inflammatory cytokines and the host metabolism. Depending on the type of cancer treatment (either curative or palliative), the clinical condition of the patient and nutritional status, adequate and patient-tailored nutritional intervention should be prescribed (diet counseling, oral supplementation, enteral or total parenteral nutrition). Nutritional support has been widely advocated as adjunctive therapy for a variety of underlying illnesses, including surgery and medical oncotherapy (radiation or chemotherapy for cancer). Glutamine, n-3 fatty acids and probiotics/prebiotics are therapeutic factors that potentially modulate gastrointestinal toxicity related to cancer treatments. Enteral and parenteral nutrition may help improve patient survival, functional status and QoL, yet the benefits appear to be primarily limited to patients with good functional status and with gastrointestinal disease affecting nutritional intake. Parenteral nutrition offers the possibility of increased or maintenance of the nutrient intake in patients for whom normal food intake is inadequate and for whom enteral nutrition is not feasible, is contraindicated or is not accepted by the patient. This article reviews evidence on issues relevant to enteral and parenteral nutrition in patients with cancer.

29 January 2024 in Current Nutrition Reports
Verified
Journal Article
Open access
PDF file
YAYasemin Açar
Yasemin Açar
GAGamze AKBULUT
Gamze AKBULUT
Purpose of Review: The first stages of human life, which include the fetal period, infancy, and early childhood, are the most critical for human growth and development. This is the most vulnerable phase to health challenges due to the immature immune system and rapid development. Mycotoxins such as aflatoxins, ochratoxin A, patulin, fumonisins, zearalenone, and deoxynivalenol are secondary metabolites secreted by various fungal species, primarily Aspergillus, Fusarium, Penicillium, and Alternaria. Aflatoxins are one of the major mycotoxins produced in cereals and cereal-based foods by several species of Aspergillus, mainly Aspergillus flavus. In this context, this review provides a brief overview of the occurrence, exposure, legal regulations, and health effects of aflatoxins (B1, B2, G1, G2, and M1) in cereal-based baby foods and breast milk. Recent Findings: Human aflatoxin exposure in utero and through breast milk, infant formulas, cereals, and cereal-based foods has been linked to various health consequences, including adverse birth outcomes, impaired growth and development, immune system suppression, and hepatic dysfunction. Recent evidence suggests that especially infants and children are more susceptible to aflatoxins due to their lower body weight, lowered capacity to detoxify harmful substances, more restrictive diet, immature metabolism and elimination, and faster rates of growth and development. Summary: It is essential for both food safety and infant and child health that aflatoxins in cereal and cereal-based products are precisely detected, detoxified, and managed.

14 July 2022 in Journal of the American Nutrition Association
Verified
Journal Article
Closed access
GDGamze Yurtdaş Depboylu
Gamze Yurtdaş Depboylu
NTNilüfer Acar Tek
Nilüfer Acar Tek
GAGamze AKBULUT
Gamze AKBULUT
ZGZerin Günel
Zerin Günel
BKBetül Kamanlı
Betül Kamanlı
The objective of this study was to evaluate the relationship between FC and physical activity, dietary intake and malnutrition in the elderly.A cross-sectional study was conducted on 883 adults age...

1 September 2020 in Gulhane Medical Journal
Verified
Journal Article
Closed access
EÜE. Nüket Ünsal
E. Nüket Ünsal
GAGamze AKBULUT
Gamze AKBULUT
HEHarun Erdal
Harun Erdal

22 October 2012 in Renal Failure
Verified
Journal Article
Closed access
GAGamze AKBULUT
Gamze AKBULUT
NŞNevin Şanlıer
Nevin Şanlıer
SISalih İnal
Salih İnal
NTNilüfer Acar Tek
Nilüfer Acar Tek
KÖKürşad Öneç
Kürşad Öneç
YEYasemin Erten
Yasemin Erten
Introduction: This study was planned to investigate the relation between dietary macronutrient status and anthropometric measurements in peritoneal dialysis (PD) patients. Materials and methods: A total of 28 clinically stable patients were enrolled in this study. All patients were taken a dietary therapy according to the guidelines of the American Journal of Kidney Foundation for 12 weeks. The anthropometric measurements were taken by bioelectrical impedance analyzer. The daily macronutrient intakes of the patients were calculated by the food consumption records. Results: The mean age was 48.3 ± 13.10 years [56.3 ± 7.41 years for males (n = 14) and 40.3 ± 12.84 years for females (n = 14)]. There were significant changes in fat percentage (%), total body water (TBW; %, L), extracellular water (ECW; %, L), basal metabolic rate over body weight (BMR/BW), and body fat mass index (BMFI) in males (p < 0.05), but there was no change in females (p > 0.05). The daily dietary energy and protein intakes were under the recommended level in the study period. Conclusion: Patients undergoing PD frequently have low intakes of protein and energy. It is recommended that individuals undergoing PD periodically maintain 3-day dietary records followed by dietary interviews conducted by a dietitian.

21 October 2023 in Current Nutrition Reports
Verified
Journal Article
Closed access
PDF file
OYOzge Yesildemir
Ozge Yesildemir
GAGamze AKBULUT
Gamze AKBULUT