Surface wettability is a critical factor influencing the biological performance of orthopedic Ti implants. The native TiO₂ film on Ti undergoes changes in wettability under ultraviolet (UV) irradiation. However, the limited tissue penetration of UV light compared with near-infrared (NIR) light restricts its potential clinical application. In this study, a black TiO₂ (b-TiO₂) coating with NIR-responsive wettability was fabricated directly on a Ti substrate using a one-step atmospheric plasma spraying process. Under 808 nm NIR irradiation, the water contact angle of the b-TiO₂ coating increased from 0° to 154.4 ± 4.0°, indicating a transition from a superhydrophilic to a stable superhydrophobic state. FTIR and XPS analyses showed that NIR-induced photothermal heating promoted the removal of surface hydroxyl groups and the passivation of oxygen-deficient sites, thereby driving the wettability transition. Among TiO₂ coatings with hydrophilic, intermediate-wettability, and hydrophobic surfaces, the hydrophobic coating effectively directed macrophage polarization toward the anti-inflammatory M2 phenotype and delivered slightly superior osteoblast activity. It also markedly inhibited Staphylococcus aureus adhesion, achieving an anti-adhesion efficiency of 98.61%. These findings demonstrate that NIR irradiation can regulate the wettability of plasma-sprayed b-TiO₂ coatings and provide concurrent immunomodulatory and antibacterial effects. This approach may support the development of light-responsive surfaces for orthopedic implants.