Alfonso J. Rodriguez-Morales

Dr. Alfonso J. Rodriguez-Morales

Fundacion Universitaria Autonoma de las Americas
orcid

Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2020 in Travel Medicine and Infectious Disease
Verified
Journal Article
Closed access
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
JCJaime A. Cardona-Ospina
Jaime A. Cardona-Ospina
EGEstefanía Gutiérrez-Ocampo
Estefanía Gutiérrez-Ocampo
RVRhuvi Villamizar-Peña
Rhuvi Villamizar-Peña
YHYeimer Holguin-Rivera
Yeimer Holguin-Rivera
Ranjit SahRanjit Sah
Ranjit Sah

16 September 2020 in Clinical Microbiology Reviews
Verified
Journal Article
Open access
PDF file
Kuldeep DhamaKuldeep Dhama
Kuldeep Dhama
Khan SharunKhan Sharun
Khan Sharun
RTRuchi Tiwari
Ruchi Tiwari
Shubhankar SircarShubhankar Sircar
Shubhankar Sircar
SBSudipta Bhat
Sudipta Bhat
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
In recent decades, several new diseases have emerged in different geographical areas, with pathogens including Ebola virus, Zika virus, Nipah virus, and coronaviruses (CoVs). Recently, a new type of viral infection emerged in Wuhan City, China, and initial genomic sequencing data of this virus do not match with previously sequenced CoVs, suggesting a novel CoV strain (2019-nCoV), which has now been termed severe acute respiratory syndrome CoV-2 (SARS-CoV-2). Although coronavirus disease 2019 (COVID-19) is suspected to originate from an animal host (zoonotic origin) followed by human-to-human transmission, the possibility of other routes should not be ruled out.

1 May 2020 in Travel Medicine and Infectious Disease
Verified
Journal Article
Closed access
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
VGViviana Gallego
Viviana Gallego
JAJuan Pablo Escalera Antezana
Juan Pablo Escalera Antezana
CMClaudio A. Méndez
Claudio A. Méndez
Lysien Ivania ZambranoLysien Ivania Zambrano
Lysien Ivania Zambrano
SCSergio Cimerman
Sergio Cimerman

1 January 2020 in Travel Medicine and Infectious Disease
Verified
Journal Article
Closed access
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
KMKirsten MacGregor
Kirsten MacGregor
SKSanch Kanagarajah
Sanch Kanagarajah
DPDipti Patel
Dipti Patel
PSPatricia Schlagenhauf
Patricia Schlagenhauf

1 January 2020 in Veterinary Quarterly
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Journal Article
Open access
RTRUCHI TIWARI
RUCHI TIWARI
Kuldeep DhamaKuldeep Dhama
Kuldeep Dhama
Khan SharunKhan Sharun
Khan Sharun
MYMohd Iqbal Yatoo
Mohd Iqbal Yatoo
Yashpal Singh MalikYashpal Singh Malik
Yashpal Singh Malik
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
Coronavirus disease 2019 (COVID-19), has spread over 210 countries and territories beyond China shortly. On February 29, 2020, the World Health Organization (WHO) denoted it in a high-risk category, and on March 11, 2020, this virus was designated pandemic, after its declaration being a Public Health International Emergency on January 30, 2020. World over high efforts are being made to counter and contain this virus. The COVID-19 outbreak once again proves the potential of the animal-human interface to act as the primary source of emerging zoonotic diseases. Even though the circumstantial evidence suggests the possibility of an initial zoonotic emergence, it is too early to confirm the role of intermediate hosts such as snakes, pangolins, turtles, and other wild animals in the origin of SARS-CoV-2, in addition to bats, the natural hosts of multiple coronaviruses such as SARS-CoV and MERS-CoV. The lessons learned from past episodes of MERS-CoV and SARS-CoV are being exploited to retort this virus. Best efforts are being taken up by worldwide nations to implement effective diagnosis, strict vigilance, heightened surveillance, and monitoring, along with adopting appropriate preventive and control strategies. Identifying the possible zoonotic emergence and the exact mechanism responsible for its initial transmission will help us to design and implement appropriate preventive barriers against the further transmission of SARS-CoV-2. This review discusses in brief about the COVID-19/SARS-CoV-2 with a particular focus on the role of animals, the veterinary and associated zoonotic links along with prevention and control strategies based on One-health approaches.

13 May 2020 in JMIR Public Health and Surveillance
Verified
Journal Article
Open access
RSRam Kumar Singh
Ram Kumar Singh
MRMeenu Rani
Meenu Rani
Akshaya BhagavathulaAkshaya Bhagavathula
Akshaya Bhagavathula
Ranjit SahRanjit Sah
Ranjit Sah
Alfonso J. Rodriguez-MoralesAlfonso J. Rodriguez-Morales
Alfonso J. Rodriguez-Morales
PKPavan Kumar
Pavan Kumar
Background: The coronavirus disease (COVID-19) pandemic has affected more than 200 countries and has infected more than 2,800,000 people as of April 24, 2020. It was first identified in Wuhan City in China in December 2019. Objective: The aim of this study is to identify the top 15 countries with spatial mapping of the confirmed cases. A comparison was done between the identified top 15 countries for confirmed cases, deaths, and recoveries, and an advanced autoregressive integrated moving average (ARIMA) model was used for predicting the COVID-19 disease spread trajectories for the next 2 months. Methods: The comparison of recent cumulative and predicted cases was done for the top 15 countries with confirmed cases, deaths, and recoveries from COVID-19. The spatial map is useful to identify the intensity of COVID-19 infections in the top 15 countries and the continents. The recent reported data for confirmed cases, deaths, and recoveries for the last 3 months was represented and compared between the top 15 infected countries. The advanced ARIMA model was used for predicting future data based on time series data. The ARIMA model provides a weight to past values and error values to correct the model prediction, so it is better than other basic regression and exponential methods. The comparison of recent cumulative and predicted cases was done for the top 15 countries with confirmed cases, deaths, and recoveries from COVID-19. Results: The top 15 countries with a high number of confirmed cases were stratified to include the data in a mathematical model. The identified top 15 countries with cumulative cases, deaths, and recoveries from COVID-19 were compared. The United States, the United Kingdom, Turkey, China, and Russia saw a relatively fast spread of the disease. There was a fast recovery ratio in China, Switzerland, Germany, Iran, and Brazil, and a slow recovery ratio in the United States, the United Kingdom, the Netherlands, Russia, and Italy. There was a high death rate ratio in Italy and the United Kingdom and a lower death rate ratio in Russia, Turkey, China, and the United States. The ARIMA model was used to predict estimated confirmed cases, deaths, and recoveries for the top 15 countries from April 24 to July 7, 2020. Its value is represented with 95%, 80%, and 70% confidence interval values. The validation of the ARIMA model was done using the Akaike information criterion value; its values were about 20, 14, and 16 for cumulative confirmed cases, deaths, and recoveries of COVID-19, respectively, which represents acceptable results. Conclusions: The observed predicted values showed that the confirmed cases, deaths, and recoveries will double in all the observed countries except China, Switzerland, and Germany. It was also observed that the death and recovery rates were rose faster when compared to confirmed cases over the next 2 months. The associated mortality rate will be much higher in the United States, Spain, and Italy followed by France, Germany, and the United Kingdom. The forecast analysis of the COVID-19 dynamics showed a different angle for the whole world, and it looks scarier than imagined, but recovery numbers start looking promising by July 7, 2020.