Fortunately, coronavirus disease 2019 (COVID-19) infection in pediatric populations exhibits a mild course of disease. However, a small number have recently been identified who develop a significant systemic inflammatory response, a new disease entity called multisystem inflammatory syndrome in children (MIS-C), especially after the peak of the wave in Al-Ahsa, Saudi Arabia, in early June to mid-July. In MIS-C children usually present a few days to a few weeks after recovery from COVID-19 with high grade fever, GI symptoms, Kawasaki-like picture or even toxic shock-like syndrome. Raising awareness about this disease entity is very fundamental to enable pediatricians and other health care providers to identify and manage these patients before it is too late. We describe 10 different cases of MIS-C with different risk factors and presentations.

Most ingested foreign bodies often pass through the gastrointestinal tract uneventfully; however, complications such as perforation do occur. Jejunal perforation is a known complication of abdominal trauma. While gastrointestinal tract injury due to the ingested foreign body such as a toothpick, fishbone, and battery among others are common, jejunal perforation is not very common in pediatrics. We report an unusual case of jejunal perforation that was diagnosed after a child was admitted to the pediatric intensive care unit for nonfatal drowning. A 15-month-old girl presented to our emergency room after she was found submerged in a swimming pool. She was unwitnessed for about ten minutes. At the scene, she was apneic, and cyanotic but had a pulse. Cardiopulmonary resuscitation was started and she was brought to our emergency room. She was managed for her drowning injuries and was accidentally found to have a foreign body on her abdomen by x-ray. She had no signs or symptoms of perforation, however, after questioning the parents they told us that they brought her a toy containing magnet balls about one month ago. After stabilizing her respiratory status and correcting her acidosis, an upper gastrointestinal (GI) endoscopy was done that showed jejunal perforation and multiple magnets. A consultation was done immediately for the pediatric surgery team then the perforation was repaired. High-powered magnets represent a serious health hazard if ingested due to risks of gastrointestinal perforation. It is important to have a high index of suspicion for potential injuries, especially silent ones. One of the rare complications is contained jejunal perforation.

Background and Clinical Significance: Diabetic ketoacidosis (DKA) is a common presentation of new-onset type 1 diabetes mellitus in children; however, severe DKA complicated by acute pancreatitis, dialysis-requiring acute kidney injury (AKI), severe hypertension, and neurological involvement is uncommon. Early recognition of these complications is essential because they may substantially increase morbidity and complicate standard DKA management; Case Presentation: An 11-year-old Saudi girl with morbid obesity (BMI 43 kg/m²), previously in good health, was brought to the emergency department after being found semi-conscious. She had experienced intermittent abdominal pain for five weeks and vomiting for four days. On presentation, she was critically ill, dehydrated, and confused (Glasgow Coma Scale 11/15) and exhibited Kussmaul breathing and abdominal tenderness. Laboratory investigations confirmed severe new-onset DKA, with a blood glucose level of 684 mg/dL, pH < 7.0, HbA1c 12.2% and an anion gap > 37 mEq/L. Despite standard DKA management, metabolic acidosis persisted and renal function progressively deteriorated, accompanied by oliguria and severe hypertension reaching 200 mmHg. By day 4, the patient developed anuria and marked creatinine elevation to 560 µmol/L. Brain magnetic resonance imaging demonstrated cerebral microhemorrhages in the setting of multifactorial encephalopathy. Continuous kidney replacement therapy was initiated for KDIGO stage 3 AKI with refractory metabolic acidosis. Autoimmune testing supported the diagnosis of type 1 diabetes mellitus, while renal biopsy demonstrated acute tubular injury; Conclusions: This case highlights a rare, severe multisystem presentation of pediatric DKA. Close monitoring for renal, neurological, pancreatic, and hypertensive complications is crucial, particularly when the clinical course does not improve as expected with standard therapy.