Orynkul Yessimova

Dr. Orynkul Yessimova


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 October 2025 in Molecules
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Journal Article
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JJJanar Jenis
Janar Jenis
AMAyaulym Minkayeva
Ayaulym Minkayeva
OYOrynkul Yessimova
Orynkul Yessimova
SKSaltanat Kumargaliyeva
Saltanat Kumargaliyeva
Abdul Bari ShahAbdul Bari Shah
Abdul Bari Shah
Aizhamal BaiseitovaAizhamal Baiseitova
Aizhamal Baiseitova
Artemisia albida, Artemisia leucodes, and Artemisia scopaeformis were selected for this study based on their traditional medicinal uses and phytochemical profiles. A. albida exhibited the highest level of extractive substances (20.76%) and showed the greatest concentration of water-soluble polysaccharides (2.14%). Tannins, well known for their astringency and antioxidant activity, were most abundant in A. scopaeformis (2.81%) and A. albida (1.52%). The phenolics coumarins were concentrated in A. scopaeformis (6.49%) and A. leucodes (4.46%). Among the extracts, A. leucodes exhibited the strongest antioxidant activity (DPPH IC50 = 13.53 μM, FRAP = 52.02 μmol TE/g), the highest SPF (23.24), and the most effective DNA protection (91.4%). It indicated a high level of biological effectiveness, with an SPF comparable to natural UV-protection agents and DNA protection exceeding 90%, suggesting potential. Molecular docking confirmed binding of catechin and epicatechin to glutathione peroxidase. Colloidal analysis revealed that hydrolates obtained from A. albida and A. leucodes have significant surface activity, reducing water surface tension to 40–50 mJ/m2, whereas the hydrolate from A. scopaeformis had only a minor effect. Thus, A. leucodes is a strong candidate for multifunctional antioxidant, UV-protective, and skin-regenerating applications.

17 September 2026 in Polymers
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Journal Article
Open access
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MKMoldir Kerimkulova
Moldir Kerimkulova
Aitugan SabitovAitugan Sabitov
Aitugan Sabitov
KMKuanyshbek Musabekov
Kuanyshbek Musabekov
GIGulmira Issenova
Gulmira Issenova
OYOrynkul Yessimova
Orynkul Yessimova
DKDidar Kapantaikyzy
Didar Kapantaikyzy
This study investigates the effectiveness of using an interpolymer complex based on a synthetic polycation—Metacid (polyhexamethylene guanidine hydrochloride) and a natural biopolymer—chitosan for anti-erosion soil structuring in the Maktaaral district of the Turkestan region. Using the conical plastometry method, the critical concentration of structure formation in the soil suspension was determined to be 67.5%; for subsequent studies, the solid phase content was taken to be 70%. Rheological studies have revealed a pronounced synergistic effect of the combined use of Metacid and chitosan. If the initial soil–water system is characterized by low elastic moduli (E1, E2 ~ 104 Pa), then the introduction of the “Metacid–chitosan” interpolymer complex leads to a sharp strengthening of the structure: The values of E1 and E2 increase to 3.26·106–7.49·106 Pa and 1.04·106–1.46·106 Pa, respectively. The mechanical stability limit increases by more than twofold, reaching 2000–2500 Pa. Analysis of the ζ-potential and electrical conductivity showed that the Metacid ensures a high positive charge of the complex (+21.76 … 28.69 mV), and chitosan acts as a spatial matrix. Experiments in a wind tunnel have confirmed that the “Metacid–chitosan” formulation, at an optimal concentration of 0.4%, provides effective protection of soil aggregates against wind erosion. The results obtained open up new prospects for using ecologically balanced interpolymer complexes to stabilize arable lands.