Skylights and windows are building openings that enhance human comfort and well-being in various ways. Recently, a massive drive is witnessed to replace traditional openings with building integrated photovoltaic (BIPV) systems to generate power in a bid to reduce buildings’ energy. The problem with most of the BIPV glazing lies in the obstruction of occupants’ vision of the outdoor view. In order to resolve this problem, new technology has emerged that utilizes quantum dots semiconductors (QDs) in glazing systems. QDs can absorb and re-emit the incoming radiation in the desired direction with the tunable spectrum, which renders them favorable for building integration. By redirecting the radiation towards edges of the glazing, they can be categorized as luminescent solar concentrators (QD-LSCs) that can help to generate electricity while maintaining transparency in the glazing. The aim of this paper is to review the different properties of core/shell quantum dots and their potential applications in buildings. Literature from various disciplines was reviewed to establish correlations between the optical and electrical properties of different types, sizes, thicknesses, and concentration ratios of QDs when used in transparent glazing. The current article will help building designers and system integrators assess the merits of integrating QDs on windows/skylights with regards to energy production and potential impact on admitted daylighting and visual comfort.