Prof. J.C. Espín (CEBAS-CSIC, Murcia, Spain) is a highly-cited researcher (from 2018 to present) who has developed an active research program to understand the high interindividual variability behind the consumption of dietary bioactives. With over 25 years of experience, he aims to unravel the complex interplay between polyphenols and human health through cutting-edge omic methodologies and multidisciplinary approaches. Core Expertise: • Biological Activity: Effects in preclinical models and human clinical trials. • Polyphenols-Gut Microbiota Interactions: Two-way relationship between polyphenols and gut microbiota (metabolism and functional implications). • Precision Health Approaches: Personalized strategies tailored to individual polyphenol-related metabotypes. • Bidirectional translational research: First in vivo, then in vitro, and back to in vivo. Unveiling physiologically relevant mechanisms. • Bioavailability and Metabolism: Targeted and non-targeted metabolomics (pharmacokinetics and tissue distribution).