As of the middle of April 2020, the unprecedented COVID-19 pandemic has claimed more than 137,000 lives (https://coronavirus.jhu.edu/map.html). Because of its extremely fast spreading, the attention of the global scientific community is now focusing on slowing down, containing and finally stopping the spread of this disease. This requires the concerted action of researchers and practitioners of many related fields, raising, as always in such situations the question, of what kind of research has to be conducted, what are the priorities, how has research to be coordinated and who needs to be involved. In other words, what are the characteristics of the response of the global research community on the challenge? In the present paper, we attempt to characterise, quantify and measure the response of academia to international public health emergencies in a comparative bibliometric study of multiple outbreaks. In addition, we provide a preliminary review of the global research effort regarding the defeat of the COVID-19 pandemic. From our analysis of six infectious disease outbreaks since 2000, including COVID-19, we find that academia always responded quickly to public health emergencies with a sharp increase in the number of publications immediately following the declaration of an outbreak by the WHO. In general, countries/regions place emphasis on epidemics in their own region, but Europe and North America are also concerned with outbreaks in other, developed and less developed areas through conducting intensive collaborative research with the core countries/regions of the outbreak, such as in the case of Ebola in Africa. Researches in the fields of virology, infectious diseases and immunology are the most active, and we identified two characteristic patterns in global science distinguishing research in Europe and America that is more focused on public health from that conducted in China and Japan with more emphasis on biomedical research and clinical pharmacy, respectively. Universities contribute slightly less than half to the global research output, and the vast majority of research funding originates from the public sector. Our findings on how academia responds to emergencies could be beneficial to decision-makers in research and health policy in creating and adjusting anti-epidemic/-pandemic strategies.

Open Access (OA) emerged as an important transition in scholarly publishing worldwide during the past two decades. So far, this transition is increasingly based on article processing charges (APC), which create a new paywall on the researchers’ side. Publishing is part of the research process and thereby necessary to perform research. This study analyses the global trends towards paying to perform research by combing observed trends in publishing from 2015 to 2020 with an APC price list. APC expenses have sharply increased among six countries with different OA policies: the USA, China, the UK, France, the Netherlands, and Norway. The estimated global revenues from APC among major publishers now exceed 2 billion US dollars annually. Mergers and takeovers show that the industry is moving towards APC-based OA as the more profitable business model. Research publishing will be closed to those who cannot make an institution or project money payment. Our results lead to a discussion of whether APC is the best way to promote OA.