The main purpose of this study is to assess seismic risk and present earthquake loss scenarios for the city of Imzouren, in northern Morocco. An empirical approach was chosen to assess the seismic vulnerability of the existing buildings, using the Vulnerability Index Method (RISK-UE), and considering two earthquake scenarios (deterministic and probabilistic). Special concern was given to the seismic vulnerability in Imzouren since the 2004 earthquake (24 February, mw = 6.4) that struck the region and caused substantial damage. A site investigation was conducted in the city targeting more than 3000 residential buildings, which had been closely examined and catalogued to assess their seismic vulnerability. The results of the seismic risk assessment in the city are represented through damage to the buildings, harm to the population and economic loss. Generally, the results obtained from the deterministic approach are in agreement with the damage caused by the 2004 earthquake.