Amaç: Çalışmamızda, olası risk faktörlerinin birikimli etkisinin madde bağımlılığı gelişmesinde tek tek risk faktörlerinin varlığından daha etkili olduğu hipotezi test edilmiştir. Yöntem: Çalışmaya 200 madde bağımlısı, 200 sağlıklı kontrol dahil edilmiştir. Deneklere SCID-I klinik görüşme, sosyodemografik veri formu, Rosenberg Benlik Saygısı Ölçeği, Ebeveynlik Stilleri Ölçeği uygulandı. Aile ve çocukluk yaşamı ile ilgili riskleri belirlemek için bir anket formu verildi. Risk faktörü olarak 14 değişken belirlendi. Örneklem yüksek ve düşük risk grubu olarak ikiye ayrıldı. Bulgular: 14 yaşından sonra ebeveyn kaybı ve ebeveynden ayrılık yaşama, aile ilişkilerini “kötü” olarak tanımlama, ailede madde bağımlılığı varlığı, düşük benlik saygısı, babanın ilgi / kabul eksikliği madde bağımlılarında sağlıklı kontrollere göre daha yaygındı. Sağlıklı kontrollerde 13 yaşından önce ebeveynden ayrılma ve sürekli aile kavgası madde bağımlılarına göre daha yüksek oranda bildirilmişti. Bağımlılığın gelişiminde anne kontrol boyutu, baba kabul boyutu ve benlik saygısının etkisi yüksek olarak belirlendi. Tartışma: Risk faktörleri tek tek ele alındığında madde bağımlılığı grubu dezavantajlı durumdayken, birikimli risk faktörleri bağlamında her iki grupta risk oranı eşitlenmektedir. Bu durum ‘’direngenlik’’ kavramını akla getirmektedir. Sağlıklı kontrollerin madde bağımlılığı geliştirmemeleri, çocukluktan itibaren karşılaştıkları olumsuz yaşam koşullarına karşı uygun baş etme becerilerini geliştirmiş olabilecekleri şeklinde yorumlanmıştır. Madde bağımlılığının önlenmesinde risk faktörlerinin azaltılmasının yanı sıra, direngenliği artıracak uygulamalara odaklanmak uygun bir yaklaşım olacaktır.

Background and Aims: The significant role of cultural influences on self-construction is also reflected in how individuals experience and express psychological distress. Somatization, the display of mental issues through physical symptoms, is less common in cultures with an autonomous self-construal typical of Western societies. While Turkey is traditionally considered a relational-collectivist society, Western Turkey exhibits higher levels of autonomous self-construal due to Westernization and economic growth. Our study explored how self-construal affects somatization in Bursa (west) and Mardin (east). Clinicians will thus, take more care of the symptoms of mental distress in patients from different cultures. Method: One hundred twenty consecutive patients were selected from those who applied to psychiatry outpatient clinics in Bursa and Mardin. Sociodemographic data form, the Autonomic-Relational Self-Scale (ARSS), Brief Symptom Inventory (BSI-53), and Diagnostic Criteria for Psychosomatic Research (DCPR). were applied to patients who volunteered to participate in the study. Results: Results showed higher somatization in Mardin and more disease phobia in Bursa. In the autonomy and relatedness dimensions of the self, autonomy was significantly higher in the Bursa group. Conclusion: These results support the idea that a relational self-construal is linked to more somatization. A negative correlation between somatization and factors like interpersonal sensitivity, anxiety, and autonomy suggests that an independent self-construal might protect against somatization. The study also emphasizes the role of cultural context in mental health.

Objectives: This study aimed to determine post-traumatic growth and its predictors in female relatives of patients with methamphetamine use disorder. Methods: The volunteers in our study consisted of 80 adult women who were first-degree relatives of male patients diagnosed with MUD. The Post-Traumatic Growth Inventory, the Hospital Anxiety-Depression Scale, the Impact of Events Scale , and the short form of the Coping with Stressful Situations Inventory were given to the relatives of the patients. Results: In our study, being employed and being married were found to affect task-oriented coping and changes in self-perception positively. Task-oriented coping or seeking emotional support from others predicted higher PTG. Task-oriented coping was positively associated with emotional coping and a change in the philosophy of life. The regression analysis determined that task-oriented and avoidant coping mechanisms were the best predictors of post-traumatic growth. Conclusions: The findings suggest that environmental and personal factors, such as being married, being employed, and the quality of social relationships that emerge with emotional and instrumental support, influence the experience of life crises. In addition, the duration of methamphetamine uses, the problem's, and the search for solutions were all associated with higher post-traumatic growth. Thus, the results of this study demonstrate that task-oriented coping, seeking emotional support, and the duration of methamphetamine use may contribute to post-traumatic growth.

Objectives: The aim of this study was to compare serum uric acid levels in patients with methamphetamine and synthetic cannabinoid use disorders pre- and post-detoxification treatment with healthy controls. Secondly, to determine the relationship between the serum uric acid levels of the cases and the severity of the addiction. Methods: Fifty methamphetamine, 50 synthetic cannabinoids, and 40 healthy controls were evaluated on the specified dates. Venous blood samples were taken from the participants to measure serum uric acid and creatinine levels. The arrangement was made by taking the Uric acid/creatinine ratio to neutralize the confounding effect of kidney functions. The Addiction Profile Index was applied to determine the severity of substance abuse in the case group. Results: A statistically significant difference was found between the uric acid values of all three groups when the One-way ANOVA test was performed (p < 0.001). UA values were significantly lower in the case groups than in the healthy control group. When the substance use characteristics of the case groups were compared, a statistically significant difference was found in the duration of substance use (p < 0.010) and motivation (p = 0.031) subtests. Duration of substance use and craving were higher in the synthetic substance group, and motivation was higher in the methamphetamine group. According to the Pearson analysis, the severity of addiction was deduced not to be correlated with serum uric acid and uric acid/creatinine levels in both case groups. Conclusions: Serum uric acid and uric acid/creatinine levels were found to be statistically significantly lower in individuals with methamphetamine and synthetic cannabinoid exposure compared to healthy controls. In this study, it was thought that the lower uric acid levels in the case group compared to the control group may be due to the use of uric acid as an antioxidant or a decrease in purinergic transformation. Future studies may focus on making this distinction.

This study aims to investigate the validity and reliability of the Turkish adaptation of the 16-item Risk of Relapse Assessment Scale (RRAS) for methamphetamine abusers. A total of 160 patients diagnosed with methamphetamine use disorder were included in this study to evaluate the validity and reliability of the scale. The comparison of the relationship between the Risk of Relapse Assessment Scale, the Substance Craving Scale, and the Relapse Prediction Scale was also carried out. The validity of the Risk of Relapse Assessment Scale was examined in the first step by exploratory factor analysis. The suitability of the data for exploratory factor analysis was evaluated by Kaiser–Meyer–Olkin test and Barlett’s test. Cronbach’s α coefficient and corrected item-total correlation value were used to test the reliability of the scale. The validity results of Risk of Relapse Assessment Scale were tested by confirmatory factor analysis. The significance level was set at P < .05 for all analyses. Considering the examination of the internal consistency values of the Risk of Relapse Assessment Scale, Cronbach’s α value was detected to be 0.90, and Cronbach’s α value of the subscales ranged from 0.72 to 0.90. The study determined that the goodness of fit values for RRAS were χ ²/df =2.13, P < .001, goodness of fit index = 0.88, comparative fit index = 0.92, normed fit index = 0.86, Trucker–Lewis index = 0.90, root mean square error of approximation = 0.08, and standardized root mean squared residual = 0.06. Our findings demonstrate that Risk of Relapse Assessment Scale is a valid and reliable measurement tool for assessing the risk of methamphetamine relapse in Turkish.

Kadın ve erkeklerin biyopsikososyal açıdan farklı özellikler taşımaları yanı sıra toplumsal değişim süreçleri eşlerin evlilik doyumunu etkilemektedir. Bu çalışmada; erkeklerin evlilik doyumlarının kadınlara göre daha düşük bulunacağı, hayata küsme düzeyi yüksek olanların evlilik doyumlarının düşük olacağı, evlilik doyumu düşük olanların psikiyatrik ölçek puanlarının daha yüksek bulunacağı hipotezlerinin test edilmesi amaçlandı. Tüm katılımcılara sosyodemografik veri formu, yaşam olayları tarama listesi, kısa semptom envanteri (KSE), travma sonrası hayata küsme bozukluğu (TSHKB) ölçeği, evlilik yaşamı ölçeği (EYÖ) uygulandı. Örneklemin %51.8’inin (n=352) kadın, %48.2’sinin (n=327) erkeklerden oluştuğu, yaş ortalamasının 39.57±7.91, EYÖ ortalamasının 35.80±8.68, TSHKB ölçeği ortalamasının 32.06±17.62, KSE ortalamasının 47.79±38.36 olduğu belirlendi. Kadınların erkeklere göre evlilik yaşamı ölçeğinde düşük, hayata küsme bozukluğu ölçeğinde ve kısa semptom envanteri toplam puanında daha yüksek puan aldıkları saptandı. Hayata küsme bozukluğu (HKB) olan kadın ve erkek gruplarında EYÖ toplam puanları HKB olmayanlara göre istatistiksel açıdan anlamlı şekilde daha düşük bulundu (p<0.001). EYÖ yüksek ve düşük grupların HKBÖ ve KSE alt ölçek puanları arasında hem kadınlarda hem de erkeklerde istatistiksel açıdan anlamlı fark oluştu. Evlilik doyumunun düşük olması, hayata küsme ve psikiyatrik semptomatolojinin yüksek olması arasında karşılıklı bir ilişkinin varlığı düşünülebilir.