On the account of motivating fabrication of bioconvection phenomenon in various engineering and industrial systems, an attention has been devoted by researchers in current decade. Therefore, this theoretical investigation deals with the utilization of bioconvection phenomenon in flow of tangent hyperbolic nanofluid over an accelerated moving surface. It is assumed that the flow is generated due to periodically motion of the sheet. The energy equation is modified by entertaining the nonlinear thermal radiation features. The chemical reaction effects are elaborated in the concentration equation. Moreover, the significance of present flow problem increases by utilizing the thermophoresis and Brownian motion effects. The governing equations are transmuted into non-dimensional form with utilization of appropriate quantities. The analytical solution is computed by using homotopy analysis method. The implications of promising parameters on velocity profile, temperature profile, nanoparticles volume fraction and microorganisms profile is evaluated graphically. The presence of radiation parameter, thermophoresis and Brownian motion effects are more frequent for enhancement of heat transfer. The reported observations can efficiently use in the improvement of heat transfer devices as well as microbial fuel cells.