Prof. Tami Livnat is an Associate Professor in the Department of Hematology at the Faculty of Medicine and serves as the Head of the Basic Research Laboratory, the National Hemophilia Center, Thrombosis Institute of the Sheba Medical Center. She completed her Ph.D. studies at Bar-Ilan University and conducted her postdoctoral training at Tel Aviv University. Throughout her career, she has been driven by a deep-rooted passion for advancing research on thrombosis and hemostasis, with the ultimate goal of enhancing patient care. Prof. Livnat’s research encompasses two complementary facets of coagulation factor activities. Firstly, she has focused on investigating plasma-related activities to develop comprehensive laboratory assays for assessing the coagulation status of patients. This includes diagnosing rare bleeding disorders, evaluating novel therapeutic interventions, and exploring anticoagulant systems. In parallel, she has explored the cellular signaling activities induced by coagulation factors. She has been particularly fascinated by the multi-target, multi-action cytoprotective activities of the natural anticoagulant, activated protein C (APC).