This article reviews reported coupling properties of astrocytes in neural circuits, functional structures, and molecular mechanisms linked to astrocytic specialized domains and spatiotemporal specificity of Ca2+ signaling. We propose a model in which astrocytes act as a bridging mechanism from microcircuit specialization to functional connectivity of brain regions and nuclei, addressing which signals are involved, how integration is achieved, and how these processes contribute to long-term memory and brain–body dimension of consciousness. The model posits that during consciousness and cognition astrocytes and their functional structures bridge neuronal encoding of multimodal embodied perception, integrate and transmit this information, and generate lagged, low-frequency Ca2+ waves that correspond to current state of consciousness or cognition. Through a relatively global signal, astrocytes shape the dynamics of cortical connectome and act at the level of brain dynamics as a downstream bridging router for memory, thereby shaping inertial circuits of consciousness over extended timescales. At the microenvironmental level, region-specific astrocytes and their subtypes shape neural circuits through metabolic coupling based on layer-specific spatial transcriptomes, thereby reversibly shaping cellular and synaptic basis of long-term memory. Through their broad receptor repertoire, astrocytes also serve as both terminal integrators of perceptual information and a neurochemical basis for information integration. At the circuit level, syncytium-based global Ca2+ waves form a global signal that locally and specifically influences cortical activity while globally regulating it, thereby coordinating cortical connectivity and spatial transcriptional profiles associated with consciousness. In embodied consciousness, astrocytes bridge bidirectional communication between consciousness as brain–body synchrony and bodily rhythms such as blood flow and respiration via neurovascular coupling and global signals.