Guanglin Chen

Dr. Guanglin Chen


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 August 2025 in Neurosurgical Review
Verified
Journal Article
Open access
PDF file
TLTao Liu
Tao Liu
SHSen Han
Sen Han
NZNan Zhang
Nan Zhang
JSJianhao sun
Jianhao sun
YZYouzhi Zhou
Youzhi Zhou
GCGuanglin Chen
Guanglin Chen
Lumbar disc herniation (LDH) is a prevalent spinal disorder affecting 20–40% of the population. This study compared the clinical efficacy of two minimally invasive techniques, one-hole split endoscopy (OSE) and unilateral biportal endoscopy (UBE), for treating single-level LDH. A retrospective analysis of 217 patients (OSE: 118; UBE: 99) treated between April 2021 and January 2025 demonstrated that while both techniques were effective, OSE offered several advantages. Incision lengths were shorter in the OSE group (2.20 ± 0.33 cm vs. 2.91 ± 0.33 cm; p < 0.001), and fewer intraoperative fluoroscopy sessions were required (2.05 ± 0.21 vs. 2.59 ± 0.59; p < 0.001). Postoperative assessments revealed lower Oswestry Disability Index(ODI) scores (19.40 ± 2.81 vs. 20.87 ± 2.88; p = 0.003) and reduced visual analog scale(VAS) scores for low back pain (1.87 ± 0.68 vs. 2.24 ± 0.58; p = 0.002) in the OSE group at 7 days. The cross-sectional area of the multifidus muscle decreased less in OSE (104.71 ± 36.10) compared to UBE (268.85 ± 40.00; p < 0.001). Complication rates were similar, with no major adverse events such as infections or nerve injuries. The minimally invasive nature of OSE may contribute to improved patient outcomes and satisfaction. Further large-scale, long-term studies are warranted to validate these findings and assess the long-term efficacy of OSE in spinal surgery. Clinical trial number: Not applicable.

31 August 2026 in BMC Musculoskeletal Disorders
Verified
Journal Article
Open access
PDF file
HLHaonan Li
Haonan Li
YZYubo Zhou
Yubo Zhou
YXYawei Xu
Yawei Xu
YJYuheng Jin
Yuheng Jin
MGMiao Ge
Miao Ge
GCGuanglin Chen
Guanglin Chen
Kümmell disease has traditionally been defined as delayed post-traumatic vertebral collapse following a symptom-free interval. Contemporary understand