Background: Global longitudinal strain (GLS) echocardiography is a new technique that can be used to detect an early left ventricular dysfunction in various heart diseases . Systemic hypertension is a major risk factor for cardiovascular accidents. The early management of its complication on the heart plays an important role in the outcome of the disease. Hypertension is associated with changes in several aspects of left ventricular structure, function, and systolic strains. Various echocardiographic techniques are used to evaluate left ventricular function in hypertensive patients. Objectives: To evaluate the effectiveness of speckle tracking global left ventricular strain percentage (GLVS%) in the assessments of left ventricular systolic function in comparison to conventional echocardiography in middle -aged hypertensive patients. Patients and Methods: The study was conducted from December 2017 till November 2018 at the Department of Echocardiography and Catheterization / Baghdad Teaching Hospital – Medical C ity,Baghdad, Iraq. One hundred and four hypertensive patients classified as ; group I that involved patients with reversed E/A ratio on PW Doppler with reversed Pulsed Wave ( PW) tissue Doppler study and group II with patients having normal E/A ratio on PW Doppler and reversed Eprime/A prime on PW tissue Doppler study . The control (group III) recruited from the relative of the patients included 104 sex and age -matched healthy individuals . A detailed history with the recommended investigations and blood pressure measurements was performed for all participants. Additionally, echocardiography examination was implemented using standard methods, considering eftventricle (LV) internal dimension, LVejection fraction percentage (LV EF%) , LV diastolic function using PW Doppler and lateral mitralannular tissue Doppler Sprime,Mitral annular plane systolic excursion (MAPSE) and global LVspeckle tracking strain percentage (GLVS%). Results: Group I included 76 patients with a mean age of (48 ± 6.6 years) and group II included 28 patients with a mean age of (48 ± 6.6 years). A ll the participants had normal EF% (> 60%), MAPSE (>13 mm), and S prime (> 9 cm /sec) while there were a significantly decreased GLVS% in the diseased groups in comparison to the control one (P < 0.005) being less in group II (-14 ± 1 %) than in Group I (- 16 ± 1 %) . In addition to a significant negative linear correlation between GL V S% with that of pulse pressure and IVST respectively ( p=0.04) and with that of E/A ratio and E/E prime ratio (p=0.001). Conclusions: GLVS% is a better method in the assessment of LV systolic function in inmiddle- aged hypertensive patients than conventional echo methods since it could detect an early impairment in LV systolic function despite preserved LV systolic function measured by the conventional echo methods
Background: Transseptal puncture is routinely performed to access the left atrium during catheter ablation of left atrial tachyarrhythmias. Although iatrogenic atrial septal defects (iASDs) frequently occur after the procedure, factors influencing delayed defect closure remain incompletely understood. Myocardial injury induced by radiofrequency (RF) ablation results in the release of cardiac troponin into the circulation and may reflect the extent of procedural tissue injury. Methods: This prospective study included patients who underwent RF ablation for left atrial arrhythmias at the Iraqi Center for Heart Diseases in collaboration with the College of medicine, University of Baghdad between March 2023 and April 2024. Serum troponin concentrations, procedural duration, and echocardiographic assessment of iASD size were evaluated prospectively to determine their association with delayed atrial septal defect closure over a period of 3–6 months. Results: Forty-seven patients were enrolled (mean age, 36.28 ± 10.34 years; 48.9% male). A significant positive association was observed between iASD size and serum troponin level (p < 0.001). For each unit increase in post-procedure troponin, the likelihood of ASD presence increases by more than two-fold at 3–6 months. Larger septal defects were also associated with longer procedural duration. Conclusions: Elevated serum troponin concentration following RF ablation is associated with larger iatrogenic atrial septal defects and may serve as a useful predictor of delayed iASD closure during the first six months of follow-up.