Introduction: The coronavirus disease 2019 (COVID-19) is a global pandemic which may affect multiple organs and systems including testes and disrupt the gonadal functions. The current study aimed to evaluate the effect of COVID-19 on the semen parameters and sex-related hormone levels in infertile men. Methods: The study included 21 patients who were evaluated in Ankara City Hospital, Andrology Clinic, for male infertility and have had the diagnosis of COVID-19. All the patients were evaluated in terms of semen parameters. The follicle-stimulating hormone, luteinizing hormone, and testosterone (T) levels were also evaluated in 8 of the patients. The results were presented through 2 dependent group analyses, based on the data of the patients collected before and after the diagnosis of COVID-19. Results: None of the patients needed to be hospitalized at any time through the course of COVID-19. There was a significant decrease in semen volume, percentage of total motility, percentage of progressive motility, and normal sperm morphology after COVID-19 (3 [1–8] vs. 2.5 [1.5–5], p = 0.005; 48.6 ± 22.1 vs. 34.7 ± 20.7, p = 0.001; 35.1 ± 21.7 vs. 21.8 ± 15.9, p < 0.001; 6 [3–24] vs. 5 [3–18], p = 0.015; respectively). There was also a significant decline in T level of the patients after the diagnosis of COVID-19 (350.1 ± 115.5 vs. 289.8 ± 103.3, p = 0.009). Conclusion: COVID-19 may have unfavorable effects on the gonadal functions and may lead to further deterioration of the semen parameters in infertile men, which should be considered through the evaluation for infertility.
Mini-Invasive Surgery is a journal covers endoscopy and other minimally invasive procedures including urology, orthopedics, neurosurgery, otolaryngology, gynecology and general surgery.
In this study, we compared the weight of the prostate specimen removed after robotic radical prostatectomy with the prostate weight measured pre‐operatively by four different imaging modalities. Pre‐operative prostate weight before robotic radical prostatectomy was measured by Transabdominal Ultrasonography (TAUS), Transrectal Ultrasonography (TRUS), Abdominal Tomography (CT) and MultiparametricProstate Magnetic Resonance imaging (mpMRI). Of the 170 patients enrolled in the study, the mean age was 65.2 ± 7.08 (46–84) years and mean prostate‐specific antigen (PSA) 9.6 ± 7.7 (1.8–50). The mean post‐operative actual prostate weight was 63.1 ± 30 gr. The mean pre‐operative prostate volumes measured by TAUS, TRUS, CT and MPMRI were 64.5 ± 28.5, 49.1 ± 30.6, 54.5 ± 30.5 and 68.7 ± 31.7 ml, respectively (p < .001). Post‐operative actual prostate weight correlated with prostate weight measured by TAUS, TRUS, CT and mpMRI (r coefficient 0.776, 0.802, 0.768 and 0.825 respectively). The best of these was mpMRI. Although prostate weight measured by different imaging methods has a high correlation to predict actual prostate weight, actual prostate weight is best predicted by measurements with mpMRI. However, errors and deviations that may occur with these imaging methods should be taken into consideration.
5 October 2021 in International Journal Of Clinical Practice
Background To compare the extract of Gilaburu (Viburnum opulus Linnaeus) and Tamsulosin as a Medical Expulsive Therapy (MET) in patients with distal ureteral calcof 10 mm or less. Methods Data of 86 patients were prospectively collected. The patients were divided into 2 groups. In the first group, Viburnum opulus 1000 mg peroral 3 × 2 and diclofenac 50 mg peroral on-demand (n = 43), in the second group Tamsulosin 0.4 mg peroral 1 × 1 and diclofenac 50 mg peroral on-demand (n = 43) was given for medical expulsive therapy in patients with distal ureteral calculi. Stone expulsion rates, time until expulsion, additional analgesic requirement, need for emergency admission, need for additional treatment were evaluated. In addition, subgroup analyzes of ≤ 5 mm and 5-10 mm were also performed. Results There was no difference between the groups in terms of stone expulsion rates and time until the expulsion in all stones. Additional analgesic requirement and need for emergency admission were found to be lower in the Viburnum Opulus group (37.2% vs. 65.1%, p = 0.017 and 11.6% vs. 34.8%, p = 0.02, respectively). In subgroup analyzes, while stone expulsion rates were similar in subgroups, it was found shorter in the time until expulsion, lower additional analgesic requirement and need for emergency admission in V. Opulus group than Tamsulosin group in 5-10 mm stone size subgroup (7.1 ± 4.2 vs. 11.8 ± 5.2, p = 0.005, 32.2% vs. 77.7%, p = 0.001 and 12.9% vs. 40.7% respectively). Conclusion V. Opulus can be used effectively and safely for the treatment of MET in distal ureteral calculi.