In this article, the non-Newtonian fluid model named Casson fluid is considered. The semi-infinite domain of disk is fitted out with magnetized Casson liquid. The role of both thermophoresis and Brownian motion is inspected by considering nanosized particles in a Casson liquid spaced above the rotating disk. The magnetized flow field is framed with Navier’s slip assumption. The Von Karman scheme is adopted to transform flow narrating equations in terms of reduced system. For better depiction a self-coded computational algorithm is executed rather than to move-on with build-in array. Numerical observations via magnetic, Lewis numbers, Casson, slip, Brownian motion, and thermophoresis parameters subject to radial, tangential velocities, temperature, and nanoparticles concentration are reported. The validation of numerical method being used is given through comparison with existing work. Comparative values of local Nusselt number and local Sherwood number are provided for involved flow controlling parameters.