Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: eHealth literacy has become an important topic in the health field and related fields. Studies have found that individuals with higher eHealth literacy are more likely to use preventive care services and to have effective interactions with their physician. In addition, previous studies have shown that there is a gender difference in the utilization of physician access and outpatient services. Nevertheless, few studies have explored the associations among gender, eHealth literacy, and various determinants of health services utilization among college students. Moreover, there is a lack of studies that focus on the three levels of eHealth literacy as predictors of health services utilization. Objective: To investigate the associations among gender, eHealth literacy, and health services utilization. Methods: The eHealth Literacy Scale is a 12-item instrument designed to measure college students’ functional, interactive, and critical eHealth literacy. The Health Services Utilization Scale is a 10-item instrument developed to measure four dimensions of health services utilization by college students. A nationally representative sample of 489 valid college students in Taiwan was surveyed. We then conducted a multiple regression analysis to examine the associations among gender, eHealth literacy, and health services utilization. Results: The study found that being female negatively predicted the purpose dimension of health services utilization (t484=-2.85, P<0.01). Moreover, critical (t484=2.98-4.23, P<0.01) and interactive eHealth literacy (t484=2.43-2.89, P<0.05) predicted 3 of the health services utilization dimensions, and functional eHealth literacy predicted only the purpose dimension (t484=-2.63, P<0.01). Conclusions: This study found that participants with high interactive and critical eHealth literacy are more likely to utilize various determinants of health services. Moreover, it found that participants with low functional or high interactive eHealth literacy might have a short time interval for visiting a doctor and that females are less likely to seek preventive, illness-related and custodial care