Cloud multi-factor authentication is a critical security measure that helps strengthen cloud security from unauthorized access and data breaches. Multi-factor authentication verifies that authentic cloud users are only authorized to access cloud apps, data, services, and resources, making it more secure for enterprises and less inconvenient for users. The number of authentication factors varies based on the security framework’s architecture and the required security level. Therefore, implementing a secured multi-factor authentication framework in a cloud platform is a challenging process. In this paper, we developed an adaptive multi-factor multi-layer authentication framework that embeds an access control and intrusion detection mechanisms with an automated selection of authentication methods. The core objective is to enhance a secured cloud platform with low false positive alarms that makes it more difficult for intruders to access the cloud system. To enhance the authentication mechanism and reduce false alarms, multiple authentication factors that include the length, validity, and value of the user factor is implemented with a user’s geolocation and user’s browser confirmation method that increase the identity verification of cloud users. An additional AES-based encryption component is applied to data, which are protected from being disclosed. The AES encryption mechanism is implemented to conceal the login information on the directory provider of the cloud. The proposed framework demonstrated excellent performance in identifying potentially malicious users and intruders, thereby effectively preventing any intentional attacks on the cloud services and data.

Cancer diagnosis and treatment depend on accurate cancer-type prediction. A prediction model can infer significant cancer features (genes). Gene expression is among the most frequently used features in cancer detection. Deep Learning (DL) architectures, which demonstrate cutting-edge performance in many disciplines, are not appropriate for the gene expression data since it contains a few samples with thousands of features. This study presents an approach that applies three feature selection techniques (Lasso, Random Forest, and Chi-Square) on gene expression data obtained from Pan-Cancer Atlas through the TCGA Firehose Data using R statistical software version 4.2.2. We calculated the feature importance of each selection method. Then we calculated the mean of the feature importance to determine the threshold for selecting the most relevant features. We constructed five models with a simple convolutional neural networks (CNNs) architecture, which are trained using the selected features and then selected the winning model. The winning model achieved a precision of 94.11%, a recall of 94.26%, an F1-score of 94.14%, and an accuracy of 96.16% on a test set.