Hollow zeolite structures including sodalite spheres and hollow zeolite NaA crystals were synthesized by introducing crosslinked polyacrylamide (C-PAM) hydrogels into zeolite synthesis gels. The synthesis gels with weight compositions of 0.8SiO₂ : 1.0Al₂O₃ : 21.2Na₂O : 86.0H₂O : 7.4–28.7 acrylamide (AM) were used to produce hollow sodalite spheres. The synthesized hollow sodalite spheres had diameters of 1–5 μm and shell thicknesses of 0.5–1 μm, and the sphere diameters decreased from 5–10 μm to 1–3 μm as the amount of C-PAM increased. Hollow zeolite A crystals with sizes of 300–500 nm were grown from the synthesis gel with a weight ratio of 0.8SiO₂ : 1.0Al₂O₃ : 2.6Na₂O : 16.4H₂O : 2.6–3.8AM. The experimental results suggest that the formation of hollow zeolite structures may involve a surface-to-core crystallization process induced by crosslinked polyacrylamide networks.

Ultrasonic-microwave assisted extraction (UMAE) of Trametes orientalis polysaccharides was optimized by response surface methodology. Hepatoprotective effects of a purified T. orientalis polysaccharide (TOP-2) were evaluated by alcohol-induced liver injury model mice. The optimal UMAE parameters were indicated as below: ratio of water to raw material 28 mL/g, microwave power 114 W, extraction time 11 min. The polysaccharides yield was 7.52 ± 0.12%, which was well consistent with the predicted value of 7.54%. Pre-treatment with TOP-2 effectively increased the liver index and spleen index in alcohol-treated mice. The elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels of mice after alcohol exposure were inhibited by TOP-2 administration. The liver tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) levels have decreased significantly as a result of alcohol exposure, while pre-treatment with TOP-2 could mitigate these consequences. Furthermore, pre-treatment with TOP-2 could efficiently boost the superoxidase dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities, and observably constrain the malondialdehyde (MDA) level. The findings suggest that TOP-2 might be useful for alleviating the alcohol-induced hepatotoxicity via its antioxidant and anti-inflammatory potential.