The concept of value co-creation brings about changes in tourists’ roles from value receivers to producers. Most existing studies take value co-creation behavior as a single dimension, ignoring the role switching of tourists. Starting from the precise constitution of value co-creation behavior, this paper, utilizing the method of structural equation modeling (SEM), discusses the mechanism of the effects of tourist participation behavior and citizenship behavior on destination loyalty through each sub-dimension of perceived value. The results showed the following: (1) The participation behavior (in-role) and citizenship behavior (extra-role) of tourists affect different value dimensions. (2) The value co-created by tourists presents a hierarchical state from the primary to the higher level. Among the types of value, novelty and social value belong to the primary level while quality, economic, knowledge, and emotional value belong to the higher level. (3) Destination loyalty is driven not only by tourist behavior (in-role) but also by citizenship behavior (extra-role). Based on the perspective of role switching, this paper establishes the theoretical framework of role switching in the era of value co-creation and proposes some strategic suggestions for marketing transformation.

Tourist engagement in marketing activities for destinations has been seen as a new driving force for the sustainable development of such destinations and as an effective way to improve their brand equity. Based on the theory of value co-creation and the theory of consumer-based brand equity for destinations, this paper examines the antecedents of brand engagement and the causal paths among them and compares the estimated values of different paths with brand image, brand awareness, and brand quality as the independent variables; brand value and brand trust as the mediating variables; and brand engagement as the dependent variable, taking Shandong Province as an example. The final results show that brand image, brand awareness, and brand quality are all key antecedents of brand engagement; however, they play different roles. The total effect of brand quality is the largest, the total effect of brand awareness follows, and the total effect of brand image is the smallest. Furthermore, the mediating effect of brand value is larger than the mediating effect of brand trust. The results provide empirical support for promoting the management of brand equity for similar destinations and encouraging tourists to participate in value co-creation activities.

Destination image and safety not only affect tourist decision-making but also the sustainable development of tourist destinations. Some tourist destinations are too vulnerable to defend against emergency tourist crises, and tourists’ perceived safety can be severely biased, which is then deepened by media panic caused by the publication of excessive negative reports. This paper discusses the mechanism of perceived safety and perceived image on tourist behavioral intention, as well as the inter-group difference. Our study is based on a survey in Southern Xinjiang in which the respondents were divided into four groups. Four structural equation models were established with “perceived safety” and “perceived image” as independent variables, “destination trust” and “perceived value” as mediating variables, and “behavioral intention” as the dependent variable. The final results show that a paradox of safety perception exists in tourists’ perception of Southern Xinjiang. The perceived safety differs sharply between the tourists who have traveled to Southern Xinjiang and those who have not. The mechanism of perceived safety on tourist behavioral intention differs from that of the perceived image on tourist behavioral intention. Destination image still plays a key role in tourist traveling decision-making. The findings are of great significance for the restoration of cognitive bias, management, and marketing activities, and the sustainable development in Southern Xinjiang and similar destinations.

NLRP3 inflammasome is an important part of the innate immune system and mediates inflammatory responses and pyroptosis. A two-signal model of NLRP3 inflammasome activation has been proposed. Ionic flux?lysosomal damage?reactive oxygen species and mitochondrial dysfunction have been shown to activate the NLRP3 inflammasome.