Rationale: Accumulating evidence shows that Rho-GTPase-activating proteins (RhoGAPs) exert suppressive roles in cancer cell proliferation and metastasis. However, no study has systematically investigated the clinical significance of RhoGAPs and analyzed the functions of ARHGAP24 in hepatocellular carcinoma (HCC).

A novel balance assistance control strategy of a hip exoskeleton robot was proposed in this paper. The organic fusion of the human balance assessment and the exoskeleton balance assistance control strategy are the assurance of balance recovery. However, currently there are few human balance assessment methods that are suitable for detecting balance loss during standing and walking, and very little research has focused on exoskeleton balance recovery control. In this paper, a single step balance assessment method was proposed first, and then based on this method an "assist-as-needed" balance assistance control strategy was established. Finally, the exoskeleton balance assistance control experiment was carried out. The experiment results verified the effectiveness of the single balance assessment method and the active balance assistance control strategy.

The lower extremity exoskeleton is a device for auxiliary assistance of human movement. The interaction performance between the exoskeleton and the human is determined by the lower extremity exoskeleton’s controller. The performance of the controller is affected by the accuracy of the dynamic equation. Therefore, it is necessary to study the dynamic parameter identification of lower extremity exoskeleton. The existing dynamic parameter identification algorithms for lower extremity exoskeletons are generally based on Least Square (LS). There are some internal drawbacks, such as complicated experimental processes and low identification accuracy. A dynamic parameter identification algorithm based on Particle Swarm Optimization (PSO) with search space defined by Recursive Least Square (RLS) is developed in this investigation. The developed algorithm is named RLS-PSO. By defining the search space of PSO, RLS-PSO not only avoids the convergence of identified parameters to the local minima, but also improves the identification accuracy of exoskeleton dynamic parameters. Under the same experimental conditions, the identification accuracy of RLS-PSO, PSO and LS was quantitatively compared and analyzed. The results demonstrated that the identification accuracy of RLS-PSO is higher than that of LS and PSO.

The motion state of a quadruped robot in operation changes constantly. Due to the drift caused by the accumulative error, the function of the inertial measurement unit (IMU) will be limited. Even though multi-sensor fusion technology is adopted, the quadruped robot will lose its ability to respond to state changes after a while because the gain tends to be constant. To solve this problem, this paper proposes a strong tracking mixed-degree cubature Kalman filter (STMCKF) method. According to system characteristics of the quadruped robot, this method makes fusion estimation of forward kinematics and IMU track. The combination mode of traditional strong tracking cubature Kalman filter (TSTCKF) and strong tracking is improved through demonstration. A new method for calculating fading factor matrix is proposed, which reduces sampling times from three to one, saving significantly calculation time. At the same time, the state estimation accuracy is improved from the third-degree accuracy of Taylor series expansion to fifth-degree accuracy. The proposed algorithm can automatically switch the working mode according to real-time supervision of the motion state and greatly improve the state estimation performance of quadruped robot system, exhibiting strong robustness and excellent real-time performance. Finally, a comparative study of STMCKF and the extended Kalman filter (EKF) that is commonly used in quadruped robot system is carried out. Results show that the method of STMCKF has high estimation accuracy and reliable ability to cope with sudden changes, without significantly increasing the calculation time, indicating the correctness of the algorithm and its great application value in quadruped robot system.

The friction and stiffness properties of the terrain are very important pieces of information for mobile robots in motion control, dynamics parameter adjustment, trajectory planning, etc. Inferring the friction and stiffness properties in advance can improve the safety, adaptability and reliability, and reduce the energy consumption of the robot. This paper proposes a vision-based two-stage framework for pre-estimating physical properties of the terrain. We established a field terrain image dataset with weak annotations. A semantic segmentation network that can segment terrains at the pixel level was designed. Given that the same terrain also has different physical properties, we designed two kinds of image features, and we use a decision-making model to realize the mapping from terrain to physical properties. We trained and tested the network comprehensively, and experimented with the complete framework for estimating physical properties. The experimental results show that our framework has good performance.