Norah Defamie

Dr. Norah Defamie

Laboratoire STIM, ERL7003 CNRS-Université de Poitiers, 1 rue G. Bonnet–TSA 51 106, 86073 Poitiers, France
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Biography

I studied biochemistry at the University of Nice Sophia-Antipolis (France). In 2001, I obtained my Ph.D. degree in endocrinology, in the laboratory of Dr. Patrick Fénichel, where I worked on the expression and localization of connexin 43 (Cx43) in normal and altered spermatogenesis, with analysis of the deleterious effects of lindane. In 2002, I decided to join the Erickson team in the Neuroscience Center at Louisiana State University (New Orleans, USA) to investigate the regulation of vesicular glutamate or glutamine transporters in primary neocortical neurons. I entered the gap junction and cancer field in 2005 when I joined the group of Prof. Marc Mesnil as an assistant professor at the University of Poitiers (France). I am currently studying the implication of gap junctions and Cx43 in the invasion and dissemination of glioblastoma cells. Invasion capacity correlates with Cx43 expression level, and we show that Cx43 is implicated in the formation and function of invadopodia of human glioblastoma cells.

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