A flexible hybrid piezoelectric–pyroelectric nanogenerator has been constructed using non-woven nanofiber membranes, which can individually or simultaneously harvest mechanical and thermal energies.
Electrospinning and electrospun fibrous assemblies have attracted interest in a variety of biomedical fields including woundcare, tissue engineering and drug delivery, due to the large surface-area-to-volume ratio and high porosity of nanofibrous webs. Normally, wound dressings are manufactured well before the point of care, and then packaged and distributed for use at a later stage. More recently, in situ electrospinning of fibers directly onto wound sites has been proposed as a route to personalized wound dressing manufacture, tailored to the needs of individual patients. Practically, in situ deposition of nanofibers on to a wound could be envisaged using a portable or hand-held electrospinning device that is safe and easy to operate. This review focuses on recent advances in portable electrospinning technology and potential applications in woundcare and regenerative medicine. The main research challenges and future trends are also considered.
For effective application of electrospinning and electrospun fibrous meshes in wound dressing, we have in situ electrospun poly(vinyl pyrrolidone)/iodine (PVP/I), PVP/poly(vinyl pyrrolidone)-iodine (PVPI) complex, and poly(vinyl butyral) (PVB)/PVPI solutions into fibrous membranes by a handheld electrospinning apparatus. The morphologies of the electrospun fibers were examined by SEM, and the hydrophobicity, gas permeability, and antibacterial properties of the as-spun meshes were also investigated. The flexibility and feasibility of in situ electrospinning PVP/I, PVP/PVPI, and PVB/PVPI membranes, as well as the excellent gas permeabilities and antibacterial properties of the as-spun meshes, promised their potential applications in wound healing.
Bicomponent composite fibers, due to their unique versatility, have attracted great attention in many fields, such as filtration, energy, and bioengineering. Herein, we efficiently fabricated polyvinylidene fluoride/polyimide (PVDF/PI) side-by-side bicomponent nanofibers based on electrospinning, which resulted in the synergism between PVDF and PI, and eventually obtained the effect of 1 + 1 > 2. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were used to characterize the morphology and chemical structure of nanofibers, indicating that a large number of side-by-side nanofibers were successfully prepared. Further, the thermal stability, mechanical strength, and filtration properties of PVDF/PI were carefully investigated. The results revealed that the bicomponent nanofibers possessed both good mechanical strength and remarkable thermal stability. Moreover, the mechanical properties of PVDF/ PI were strengthened by more than twice after the heat treatment (7.28 MPa at 25 °C, 15.49 MPa at 230 °C). Simultaneously, after the heat treatment at 230 °C for 30 min, the filtration efficiency of PVDF/PI membrane was maintained at about 95.45 ± 1.09%, and the pressure drop was relatively low. Therefore, the prepared PVDF/PI side-by-side bicomponent nanofibers have a favorable prospect of application in the field of medium- and high-temperature filtration, which further expands the application range of electrospun fiber membranes.
1 April 2020 in Colloids and Surfaces B: Biointerfaces