A systematic review was conducted on the literature on feeding behaviors in Chinese families of children under 6 years old. Forty relevant publications were identified, of which 33 were published in Chinese, 7 in English. All studies were questionnaire-based and used a cross-sectional research design. Approximately half of the studies reported a score for each feeding practice/style, based on a Likert scale; the other half dichotomized these scores into a percentage of the population that reported frequent use of the behaviors. The most commonly reported feeding style of Chinese caregivers was a locally defined "active response" style that somewhat resembled authoritative parenting. The most commonly reported feeding practices were praise, encouraging trying new foods, encouragement of balanced diet and encouragement of healthy eating. Some behaviors showed a great deal of variance in prevalence between studies, which may be at least partially due to differences in methodology and how behaviors were defined. Some feeding behaviors varied in frequency depending on the child's age, although longitudinal studies are needed to better understand how these evolve over time. Child body composition was also associated with feeding behaviors use, although the direction of the association cannot be determined due to the cross-sectional nature of the research. There is still an important gap in the literature regarding the feeding behaviors of non-maternal caregivers, as grandparents often play an important role in childcare in China.
Congenital chloride diarrhea (CCD) in a newborn is a rare autosomal recessive disorder with life-threatening complications, requiring early diagnostics and treatment to prevent severe dehydration and infant mortality. SLC26A3 rs386833481 (c.392C>G; p.P131R) gene polymorphism is an important genetic determinant of CCD. Here, we report the influence of the non-synonymous SLC26A3 variant rs386833481 gene polymorphism on the function of the epithelial barrier and the potential mechanisms of these effects. We found that P131R-SLC26A3 increased dysfunction of the epithelial barrier compared with wild type SLC26A3 in human colonic Caco-2 and mouse colonic CMT-93 cells. When P131R-SLC26A3 was subsequently reverted to wild type, the epithelial barrier function was restored similar to wild type cells. Further study demonstrated that variant P131R-SLC26A3 disrupts function of epithelial barrier through two distinct molecular mechanisms: (a) decreasing SLC26A3 expression through a ubiquitination pathway and (b) disrupting a key interaction with its partner ZO-1/CFTR, thereby increasing the epithelial permeability. Our study provides an important insight of SLC26A3 SNPs in the regulation of the epithelial permeability and indicates that SLC26A3 rs386833481 is likely a causative mutation in the dysfunction of epithelial barrier of CCD, and correction of this SNP or increasing SLC26A3 function could be therapeutically beneficial for chronic diarrhea diseases.
1 January 2023 in International Journal of New Developments in Education
The "double-height" construction plan of China's vocational education reform proposes to build high-level vocational schools and high-level majors. The industry-education integration is the key task of the "double-height" construction plan, an important tool for deepening the reform of education, and a key measure to build a high level institution with Chinese characteristics and world standards. The "dual-qualification" teacher team is an important force for the internal development of higher vocational institutions and a fundamental guarantee for improving the quality of talent training. The industry-education integration is an important carrier for the construction of "dual-qualification" teachers, which realizes the organic integration of industry chain and education chain. This paper analyzes the current situation of English teachers in higher vocational institutions from the background of industry-teaching integration, and finds that there are problems such as solidified teaching concept, single knowledge structure, lack of practical ability and imperfect teacher development mechanism of college English teachers. In view of these problems, the development path of " "dual-qualification " college English teachers is proposed: College English teachers need to update their education and teaching concepts, improve their comprehensive quality, and construct a perfect development mechanism for "dual-qualification " college English teachers. We hope to promote the development of college English teachers, build an excellent "dual-qualification" college English teachers’ team, and help the construction of "double-height" construction plan for higher vocational education.
With the continuous development of China’s economy, people’s quality of life is constantly improving. As a matter of course, more and more attention is paid to home design. In particular, the space design of small apartments is welcomed by everyone. Among them, soft cloth decoration is a very popular form of home design now, which is very suitable for the design and use of small apartment. But the diversity of small family space brings difficulties to the design. The design and calculation of the simple home space in the small apartment with the RANSAC algorithm is fully satisfied with the requirements of the use of the algorithm and can achieve the accuracy of our calculation and facilitate communication with customers. The RANSAC algorithm has the powerful ability of image processing, which can help us to establish the visualization research of space design.