This paper reports the use of light-field microscopy for fast, large-scale imaging of neuronal activity in vivo. It is applied to image the entire animal in the worm and the whole brain in zebrafish. High-speed, large-scale three-dimensional (3D) imaging of neuronal activity poses a major challenge in neuroscience. Here we demonstrate simultaneous functional imaging of neuronal activity at single-neuron resolution in an entire Caenorhabditis elegans and in larval zebrafish brain. Our technique captures the dynamics of spiking neurons in volumes of ∼700 μm × 700 μm × 200 μm at 20 Hz. Its simplicity makes it an attractive tool for high-speed volumetric calcium imaging.

We report the first experimental generation and characterization of a six-photon Dicke state. The produced state shows a fidelity of $F=0.56\pm 0.02$ with respect to an ideal Dicke state and violates a witness detecting genuine six-qubit entanglement by 4 standard deviations. We confirm characteristic Dicke properties of our resource and demonstrate its versatility by projecting out four- and five-photon Dicke states, as well as four-photon Greenberger-Horne-Zeilinger and $W$ states. We also show that Dicke states have interesting applications in multiparty quantum networking protocols such as open-destination teleportation, telecloning, and quantum secret sharing.

We demonstrate phase super-resolution in the absence of entangled states. The key insight is to use the inherent time-reversal symmetry of quantum mechanics: our theory shows that it is possible to measure, as opposed to prepare, entangled states. Our approach is robust, requiring only photons that exhibit classical interference: we experimentally demonstrate high-visibility phase super-resolution with three, four, and six photons using a standard laser and photon counters. Our six-photon experiment demonstrates the best phase super-resolution yet reported with high visibility and resolution.