Several challenges are associated with e-learning systems, the most significant of which is the lack of student motivation in various course activities and for various course materials. In this study, we used machine learning (ML) algorithms to identify low-engagement students in a social science course at the Open University (OU) to assess the effect of engagement on student performance. The input variables of the study includedhighest education level,final results,score on the assessment, and the number of clicks on virtual learning environment (VLE) activities, which includeddataplus,forumng,glossary,oucollaborate,oucontent,resources,subpages,homepage,and URLduring the first course assessment. The output variable was the student level of engagement in the various activities. To predict low-engagement students, we applied several ML algorithms to the dataset. Using these algorithms, trained models were first obtained; then, the accuracy and kappa values of the models were compared. The results demonstrated that the J48, decision tree, JRIP, and gradient-boosted classifiers exhibited better performance in terms of the accuracy, kappa value, and recall compared to the other tested models. Based on these findings, we developed a dashboard to facilitate instructor at the OU. These models can easily be incorporated into VLE systems to help instructors evaluate student engagement during VLE courses with regard to different activities and materials and to provide additional interventions for students in advance of their final exam. Furthermore, this study examined the relationship between student engagement and the course assessment score.

Incorporating substantial, sustainable development issues into teaching and learning is the ultimate task of Education for Sustainable Development (ESD). The purpose of our study was to identify the confused students who had failed to master the skill(s) given by the tutors as homework using the Intelligent Tutoring System (ITS). We have focused ASSISTments, an ITS in this study, and scrutinized the skill-builder data using machine learning techniques and methods. We used seven candidate models including: Naïve Bayes (NB), Generalized Linear Model (GLM), Logistic Regression (LR), Deep Learning (DL), Decision Tree (DT), Random Forest (RF), and Gradient Boosted Trees (XGBoost). We trained, validated, and tested learning algorithms, performed stratified cross-validation, and measured the performance of the models through various performance metrics, i.e., ROC (Receiver Operating Characteristic), Accuracy, Precision, Recall, F-Measure, Sensitivity, and Specificity. We found RF, GLM, XGBoost, and DL were high accuracy-achieving classifiers. However, other perceptions such as detecting unexplored features that might be related to the forecasting of outputs can also boost the accuracy of the prediction model. Through machine learning methods, we identified the group of students that were confused when attempting the homework exercise, to help foster their knowledge and talent to play a vital role in environmental development.

Software engineering is a competitive field in education and practice. Software projects are key elements of software engineering courses. Software projects feature a fusion of process and product. The process reflects the methodology of performing the overall software engineering practice. The software product is the final product produced by applying the process. Like any other academic domain, an early evaluation of the software product being developed is vital to identify the at-risk teams for sustainable education in software engineering. Guidance and instructor attention can help overcome the confusion and difficulties of low performing teams. This study proposed a hybrid approach of information gain feature selection with a J48 decision tree to predict the earliest possible phase for final performance prediction. The proposed technique was compared with the state-of-the-art machine learning (ML) classifiers, naïve Bayes (NB), artificial neural network (ANN), logistic regression (LR), simple logistic regression (SLR), repeated incremental pruning to produce error reduction (RIPPER), and sequential minimal optimization (SMO). The goal of this process is to predict the teams expected to obtain a below-average grade in software product development. The proposed technique outperforms others in the prediction of low performing teams at an early assessment stage. The proposed J48-based technique outperforms others by making 89% correct predictions.

Retinal blood vessels, the diagnostic bio‐marker of ophthalmologic and diabetic retinopathy, utilise thick and thin vessels for diagnostic and monitoring purposes. The existing deep learning methods attempt to segment the retinal vessels using a unified loss function. However, a difference in spatial features of thick and thin vessels and a biased distribution creates an imbalanced thickness, rendering the unified loss function to be useful only for thick vessels. To address this challenge, a patch‐based generative adversarial network‐based technique is proposed which iteratively learns both thick and thin vessels in fundoscopic images. It introduces an additional loss function that allows the generator network to learn thin and thick vessels, while the discriminator network assists in segmenting out both vessels as a combined objective function. Compared with state‐of‐the‐art techniques, the proposed model demonstrates the enhanced accuracy, sensitivity, specificity, and area under the receiver operating characteristic curves on STARE, DRIVE, and CHASEDB1 datasets.

Despite continuing progress in X-ray crystallography and high-field NMR spectroscopy for determination of three-dimensional protein structures, the number of unsolved and newly discovered sequences grows much faster than that of determined structures. Protein modeling methods can possibly bridge this huge sequence-structure gap with the development of computational science. A grand challenging problem is to predict three-dimensional protein structure from its primary structure (residues sequence) alone. However, predicting residue contact maps is a crucial and promising intermediate step towards final three-dimensional structure prediction. Better predictions of local and non-local contacts between residues can transform protein sequence alignment to structure alignment, which can finally improve template based three-dimensional protein structure predictors greatly. CNNcon, an improved multiple neural networks based contact map predictor using six sub-networks and one final cascade-network, was developed in this paper. Both the sub-networks and the final cascade-network were trained and tested with their corresponding data sets. While for testing, the target protein was first coded and then input to its corresponding sub-networks for prediction. After that, the intermediate results were input to the cascade-network to finish the final prediction. The CNNcon can accurately predict 58.86% in average of contacts at a distance cutoff of 8 Å for proteins with lengths ranging from 51 to 450. The comparison results show that the present method performs better than the compared state-of-the-art predictors. Particularly, the prediction accuracy keeps steady with the increase of protein sequence length. It indicates that the CNNcon overcomes the thin density problem, with which other current predictors have trouble. This advantage makes the method valuable to the prediction of long length proteins. As a result, the effective prediction of long length proteins could be possible by the CNNcon.