Melanoma is a severe skin cancer that involves abnormal cell development. This study aims to provide a new feature fusion framework for melanoma classification that includes a novel ‘F’ Flag feature for early detection. This novel ‘F’ indicator efficiently distinguishes benign skin lesions from malignant ones known as melanoma. The article proposes an architecture that is built in a Double Decker Convolutional Neural Network called DDCNN future fusion. The network's deck one, known as a Convolutional Neural Network (CNN), finds difficult-to-classify hairy images using a confidence factor termed the intra-class variance score. These hirsute image samples are combined to form a Baseline Separated Channel (BSC). By eliminating hair and using data augmentation techniques, the BSC is ready for analysis. The network's second deck trains the pre-processed BSC and generates bottleneck features. The bottleneck features are merged with features generated from the ABCDE clinical bio indicators to promote classification accuracy. Different types of classifiers are fed to the resulting hybrid fused features with the novel 'F' Flag feature. The proposed system was trained using the ISIC 2019 and ISIC 2020 datasets to assess its performance. The empirical findings expose that the DDCNN feature fusion strategy for exposing malignant melanoma achieved a specificity of 98.4%, accuracy of 93.75%, precision of 98.56%, and Area Under Curve (AUC) value of 0.98. This study proposes a novel approach that can accurately identify and diagnose fatal skin cancer and outperform other state-of-the-art techniques, which is attributed to the DDCNN ‘F’ Feature fusion framework. Also, this research ascertained improvements in several classifiers when utilising the ‘F’ indicator, resulting in the highest specificity of + 7.34%.

A hybrid segmentation algorithm is proposed is this paper to extract the blood vessels from the fundus image of retina. Fundus camera captures the posterior surface of the eye and the captured images are used to diagnose diseases, like Diabetic Retinopathy, Retinoblastoma, Retinal haemorrhage, etc. Segmentation or extraction of blood vessels is highly required, since the analysis of vessels is crucial for diagnosis, treatment planning, and execution of clinical outcomes in the field of ophthalmology. It is derived from the literature review that no unique segmentation algorithm is suitable for images of different eye-related diseases and the degradation of the vessels differ from patient to patient. If the blood vessels are extracted from the fundus images, it will make the diagnosis process easier. Hence, this paper aims to frame a hybrid segmentation algorithm exclusively for the extraction of blood vessels from the fundus image. The proposed algorithm is hybridized with morphological operations, bottom hat transform, multi-scale vessel enhancement (MSVE) algorithm, and image fusion. After execution of the proposed segmentation algorithm, the area-based morphological operator is applied to highlight the blood vessels. To validate the proposed algorithm, the results are compared with the ground truth of the High-Resolution Fundus (HRF) images dataset. Upon comparison, it is inferred that the proposed algorithm segments the blood vessels with more accuracy than the existing algorithms.

Skin cancer can be prevalent in people of any age group who are exposed to ultraviolet (UV) radiation. Among all other types, melanoma is a notable severe kind of skin cancer, which can be fatal. Melanoma is a malignant skin cancer arising from melanocytes, requiring early detection. Typically, skin lesions are classified either as benign or malignant. However, some lesions do exist that don’t show clear cancer signs, making them suspicious. If unnoticed, these suspicious lesions develop into severe melanoma, requiring invasive treatments later on. These intermediate or suspicious skin lesions are completely curable if it is diagnosed at their early stages. To tackle this, few researchers intended to improve the image quality of the infected lesions obtained from the dermoscopy through image reconstruction techniques. Analyzing reconstructed super-resolution (SR) images allows early detection, fine feature extraction, and treatment plans. Despite advancements in machine learning, deep learning, and complex neural networks enhancing skin lesion image quality, a key challenge remains unresolved: how the intricate textures are obtained while performing significant up scaling in medical image reconstruction? Thus, an artificial intelligence (AI) based reconstruction algorithm is proposed to obtain the fine features from the intermediate skin lesion from dermoscopic images for early diagnosis. This serves as a non-invasive approach. In this research, a novel melanoma information improvised generative adversarial network (MELIIGAN) framework is proposed for the expedited diagnosis of intermediate skin lesions. Also, designed a stacked residual block that handles larger scaling factors and the reconstruction of fine-grained details. Finally, a hybrid loss function with a total variation (TV) regularization term switches to the Charbonnier loss function, a robust substitute for the mean square error loss function. The benchmark dataset results in a structural index similarity (SSIM) of 0.946 and a peak signal-to-noise ratio (PSNR) of 40.12 dB as the highest texture information, evidently compared to other state-of-the-art methods.