Xin-Juan Wu

Prof. Xin-Juan Wu

Peking Union Medical College Hospital

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 March 2020 in Psychological Medicine
Verified
Journal Article
Open access
PDF file
HBHai-Xin Bo
Hai-Xin Bo
WLWen Li
Wen Li
YYYuan Yang
Yuan Yang
YWYu Wang
Yu Wang
QZQinge Zhang
Qinge Zhang
YXYu-Tao Xiang
Yu-Tao Xiang

1 October 2020 in Journal of Affective Disorders
Verified
Journal Article
Closed access
YMYu-Fen Ma
Yu-Fen Ma
WLWen Li
Wen Li
HDHai-Bao Deng
Hai-Bao Deng
LWLei Wang
Lei Wang
YWYing Wang
Ying Wang
YXYu-Tao Xiang
Yu-Tao Xiang

12 October 2018 in PLOS ONE
Verified
Journal Article
Open access
PDF file
XWXin-Juan Wu
Xin-Juan Wu
ZLZhen Li
Zhen Li
JCJing Cao
Jing Cao
JJJing Jiao
Jing Jiao
YWYingli Wang
Yingli Wang
XWXia Wan
Xia Wan
To describe the association between major complications of immobility (pressure ulcer, pneumonia, deep vein thrombosis and urinary tract infection) during hospitalization and the patients’ health-related quality of life after discharge. The data were obtained from a multi-center study conducted in 2015. Complications of immobility during hospitalization was measured by case report form and quality of life after discharge was measured using the EQ-5D scale by telephone interview. Multilevel mixed-effects models were used to explore the association of complications and responses in the EQ-5D dimensions after controlling for important covariates. Among the 20,515 bedridden patients, 2,601(12.72%) patients experienced at least one of the major complications of immobility during hospitalization, including pressure ulcer (527, 2.57%), deep vein thrombosis (343, 1.67%), pneumonia (1647, 8.16%), and urinary tract infection (265, 1.29%). Patients with any of the four complications during hospitalization reported more problems in all EQ-5D dimensions except for pain/discomfort, and had lower mean EQ-VAS scores than those without any complications. The four complications all showed significant associations with the proportion of reported problems in certain dimensions after adjustment for confounding variables. Major complications of immobility were significantly associated with reduced health related quality of life. Prevention of complications is critical to reduce the burden of decreased quality of life for bedridden patients.

17 November 2022 in Journal of the American Medical Directors Association
Verified
Journal Article
Open access
XZXiao-Ming Zhang
Xiao-Ming Zhang
SCSimin Cao
Simin Cao
MGMaofeng Gao
Maofeng Gao
SXShiyan Xiao
Shiyan Xiao
XXXiaohua Xie
Xiaohua Xie
XWXin-Juan Wu
Xin-Juan Wu
To report the overall prevalence of social frailty among older people and provide information for policymakers and authorities to use in developing policies and social care. A systematic review and meta-analysis. We searched 4 databases (PubMed, Embase, Web of Science, and Google Scholar) to find articles from inception to July 30, 2022. We included cross-sectional and cohort studies that provided the prevalence of social frailty among adults aged 60 years or older, in any setting. Three researchers independently reviewed the literature and retrieved the data. A risk of bias tool was used to assess each study's quality. A random-effect meta-analysis was performed to pool the data, followed by subgroup analysis, sensitivity analysis, and meta-regression. From 761 records, we extracted 43 studies with 83,907 participants for meta-analysis. The pooled prevalence of social frailty in hospital settings was 47.3% (95% CI: 32.2%-62.4%); among studies in community settings, the pooled prevalence was 18.8% (95% CI: 14.9%-22.7%; P < .001). The prevalence of social frailty was higher when assessed using the Tilburg Frailty Indicator (32.3%; 95% CI: 23.1%-41.5%) than the Makizako Social Frailty Index (27.7%; 95% CI: 21.6%-33.8%) or Social Frailty Screening Index (13.4%; 95% CI: 8.4%-18.4%). Based on limited community studies in individual countries using various instruments, social frailty was lowest in China (4.9%; 95% CI: 4.2%-5.7%), followed by Spain (11.6%; 95% CI: 9.9%-13.3%), Japan (16.2%; 95% CI: 12.2%-20.3%), Korea (26.6%; 95% CI: 7.1%-46.1%), European urban centers (29.2%; 95% CI: 27.9%-30.5%), and the Netherlands (27.2%; 95% CI: 16.9%-37.5%). No other subgroup analyses showed any statistically significant prevalence difference between groups. The prevalence of social frailty among older adults is high. Settings, country, and method for assessing social frailty affected the prevalence. More valid comparisons will await consensus on measurement tools and more research on geographically representative populations. Nevertheless, these results suggest that public health professionals and policymakers should seriously consider social frailty in research and program planning involving older adults.

17 March 2021 in BMC Geriatrics
Verified
Journal Article
Open access
PDF file
XZXiao-Ming Zhang
Xiao-Ming Zhang
JJJing Jiao
Jing Jiao
JCJing Cao
Jing Cao
XHXiao-Peng Huo
Xiao-Peng Huo
CZChen Zhu
Chen Zhu
XXXiaohua Xie
Xiaohua Xie
Background: A large number of studies have explored the association between frailty and mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis was to synthesize the evidence on this issue. Methods: Three databases, PubMed, Embase, and Cochrane Library, from inception to 20th January 2021 were searched for relevant literature. The Newcastle–Ottawa Scale (NOS) was used to assess quality bias, and STATA was employed to pool the effect size by a random effects model. Additionally, potential publication bias and sensitivity analyses were performed. Results: Fifteen studies were included, with a total of 23,944 COVID-19 patients, for quantitative analysis. Overall, the pooled prevalence of frailty was 51% (95% CI: 44–59%). Patients with frailty who were infected with COVID-19 had an increased risk of mortality compared to those without frailty, and the pooled hazard ratio (HR) and odds ratio (OR) were 1.99 (95% CI: 1.66–2.38) and 2.48 (95% CI: 1.78–3.46), respectively. In addition, subgroup analysis based on population showed that the pooled ORs for hospitalized patients in eight studies and nursing home residents in two studies were 2.62 (95% CI: 1.68–4.07) and 2.09 (95% CI: 1.40–3.11), respectively. Subgroup analysis using the frailty assessment tool indicated that this association still existed when using the clinical frailty scale (CFS) (assessed in 6 studies, pooled OR = 2.88, 95% CI: 1.52–5.45; assessed in 5 studies, pooled HR = 1.99, 95% CI: 1.66–2.38) and other frailty tools (assessed in 4 studies, pooled OR = 1.98, 95% CI: 1.81–2.16). In addition, these significant positive associations still existed in the subgroup analysis based on study design and geographic region. Conclusion: Our study indicates that frailty is an independent predictor of mortality among patients with COVID-19. Thus, frailty could be a prognostic factor for clinicians to stratify high-risk groups and remind doctors and nurses to perform early screening and corresponding interventions urgently needed to reduce mortality rates in patients infected by SARS-CoV-2.

1 October 2018 in International Journal of Nursing Sciences
Verified
Journal Article
Open access
XWXin-Juan Wu
Xin-Juan Wu
JLJiaqian Li
Jiaqian Li
GLGe Liu
Ge Liu
YLYing Liu
Ying Liu
JCJing Cao
Jing Cao
ZJZhaoxia Jia
Zhaoxia Jia
This study aimed to explore the status of job satisfaction, emotional labour, core competencies and job stress and the associations of emotional labour and core competencies with the job satisfaction of nurses in China. Data were collected by using a self-designed general information questionnaire, a job satisfaction questionnaire (McCloskey/Mueller Satisfaction Scale), a nurse emotional labour questionnaire, the Competency Inventory for Registered Nurses questionnaire, and a nurse job stressor questionnaire. A total of 13,448 nurses from 92 hospitals across mainland of China were surveyed, and 11,337 respondents (84.3% response rate) completed the questionnaires. The survey results indicated that Chinese nurses had average job satisfaction (24.77 ± 5.23), moderate job stress (86.84 ± 21.12), moderate to high emotional labour experiences (55.08 ± 9.63) and high competency (195.77 ± 37.61). Multiple linear regression indicated that surface acting was negatively correlated with job satisfaction (P < 0.01), while deep acting (P < 0.01) and nurses' core competence (P < 0.01) were positively associated with job satisfaction. Besides, The results also indicated job stress, geographical distribution, hospital category, gender, work shift, only children, parenting status, monthly salary, nursing experience, professional title, hospital area were the influencing factors of job satisfaction (P < 0.05). The improvement of the emotional labour and competency of nurses may help enhance their job satisfaction.