We present evidence from a variety of physical and biological proxies for a severe drought that affected the mid-continent of North America between 4.1 and 4.3 ka. Rapid climate changes associated with the event had large and widespread ecological effects, including dune reactivation, forest fires and long-term changes in forest composition, highlighting a clear ecological vulnerability to similar future changes. Drought is also documented in the Middle East and portions of Africa and Asia, where it was similar in timing, duration and magnitude to that recorded in the central North American records. Some regions at high latitudes, including northern Europe and Siberia, experienced cooler and/or wetter conditions. Widespread mid-latitude and subtropical drought, associated with increased moisture at some high latitudes, has been linked in the instrumental record to an unusually steep sea surface temperature (SST) gradient between the tropical eastern and western Pacific Ocean (La Ninia) and increased warmth in other equatorial oceans. Similar SST patterns may have occurred at 4.2 ka, possibly associated with external forcing or amplification of these spatial modes by variations in solar irradiance or volcanism. However, changes in SST distribution bracketing the 4.2 ka event are poorly known in most regions and data are insufficient to estimate magnitude of changes in solar and volcanic forcing at this time. Further research is needed to delineate geographical patterns of moisture changes, ecological responses, possible forcing mechanisms and climatology of this severe climatic event.

Multiple lines of genetic and archaeological evidence suggest that there were major demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of sub-Saharan Africa^1–4. Inferences about this period are challenging to make because demographic shifts in the past 5,000 years have obscured the structures of more ancient populations^3,5. Here we present genome-wide ancient DNA data for six individuals from eastern and south-central Africa spanning the past approximately 18,000 years (doubling the time depth of sub-Saharan African ancient DNA), increase the data quality for 15 previously published ancient individuals and analyse these alongside data from 13 other published ancient individuals. The ancestry of the individuals in our study area can be modelled as a geographically structured mixture of three highly divergent source populations, probably reflecting Pleistocene interactions around 80–20 thousand years ago, including deeply diverged eastern and southern African lineages, plus a previously unappreciated ubiquitous distribution of ancestry that occurs in highest proportion today in central African rainforest hunter-gatherers. Once established, this structure remained highly stable, with limited long-range gene flow. These results provide a new line of genetic evidence in support of hypotheses that have emerged from archaeological analyses but remain contested, suggesting increasing regionalization at the end of the Pleistocene epoch.

Modern Homo sapiens engage in substantial ecosystem modification, but it is difficult to detect the origins or early consequences of these behaviors. Archaeological, geochronological, geomorphological, and paleoenvironmental data from northern Malawi document a changing relationship between forager presence, ecosystem organization, and alluvial fan formation in the Late Pleistocene. Dense concentrations of Middle Stone Age artifacts and alluvial fan systems formed after ca. 92 thousand years ago, within a paleoecological context with no analog in the preceding half-million-year record. Archaeological data and principal coordinates analysis indicate that early anthropogenic fire relaxed seasonal constraints on ignitions, influencing vegetation composition and erosion. This operated in tandem with climate-driven changes in precipitation to culminate in an ecological transition to an early, pre-agricultural anthropogenic landscape.

There is great uncertainty over the timing and magnitude of the termination of the African Humid Period (AHP). Spanning from the early to middle Holocene, the AHP was a period of enhanced moisture over most of northern and eastern Africa. However, beginning 8000 years ago the moisture balance shifted due to changing orbital precession and vegetation feedbacks. Some proxy records indicate a rapid transition from wet to dry conditions, while others indicate a more gradual changeover. Heretofore, humans have been viewed as passive agents in the termination of the AHP, responding to changing climatic conditions by adopting animal husbandry and spreading an agricultural lifestyle across the African continent. This paper explores scenarios whereby humans could be viewed as active agents in landscape denudation. During the period when agriculture was adopted in northern Africa, the regions where it was occurring were at the precipice of ecological regime shifts. Pastoralism, in particular, is argued to enhance devegetation and regime shifts in unbalanced ecosystems. Threshold crossing events were documented in the historical records of New Zealand and western North America due to the introduction of livestock. In looking at temporally correlated archaeological and paleoenvironmental records of northern Africa, similar landscape dynamics from the historical precedents are observed: reduction in net primary productivity, homogenization of the flora, transformation of the landscape into a shrub-dominated biozone and increasing xerophylic vegetation overall. Although human agents are not seen as the only forces inducing regime change during the termination of the AHP, their potential role in inducing large-scale landscape change must be properly contextualized against other global occurrences of neolithization.