Gonzalo Sánchez-Duffhues is a group leader and Ramon y Cajal fellow at the Nanomaterials and Nanotechnology Research Center (CINN), which is part of the Spanish National Research Council (CSIC). After completing his PhD in 2011 at the University of Córdoba (Spain), where he focused on investigating cellular targets and semi-synthetic compounds that modulate inflammatory signalling, he joined the research group led by Prof. Peter ten Dijke at the Leiden University Medical Center (NL). In Leiden, Gonzalo's research primarily focused on understanding the mechanisms by which TGF-β factors regulate cell plasticity in human diseases, with a particular emphasis on musculoskeletal disorders and cardiovascular diseases. Subsequently, he joined the group of Prof. Marie-José Goumans, where he gained a deeper understanding of how TGF-β signaling controls stem cell biology. In his recently established group at CINN, Gonzalo's main objective is to identify and target tissue-specific molecular mechanisms that underlie TGF-β-driven diseases.