Harshita Sharma

Harshita Sharma


Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2017 in Computerized Medical Imaging and Graphics
Verified
Journal Article
Closed access
HSHarshita Sharma
Harshita Sharma
NZNorman Zerbe
Norman Zerbe
IKIris Klempert
Iris Klempert
OHOlaf Hellwich
Olaf Hellwich
PHPeter Hufnagl
Peter Hufnagl

13 January 2025 in Nature Machine Intelligence
Verified
Journal Article
Closed access
PDF file
FPFernando Pérez-García
Fernando Pérez-García
HSHarshita Sharma
Harshita Sharma
SBSam Bond-Taylor
Sam Bond-Taylor
KBKenza Bouzid
Kenza Bouzid
VSValentina Salvatelli
Valentina Salvatelli
OOOzan Oktay
Ozan Oktay

20 January 2026 in Nature Medicine
Verified
Journal Article
Closed access
PDF file
SBSuhana Bedi
Suhana Bedi
HCHejie Cui
Hejie Cui
MFMiguel Fuentes
Miguel Fuentes
AUAlyssa Unell
Alyssa Unell
MWMichael Wornow
Michael Wornow
NSNigam H. Shah
Nigam H. Shah

11 May 2024
Verified
Conference Paper
Open access
NYNur Yildirim
Nur Yildirim
HRHannah Richardson
Hannah Richardson
MWMaria Teodora Wetscherek
Maria Teodora Wetscherek
JBJunaid Bajwa
Junaid Bajwa
JJJoseph Jacob
Joseph Jacob
Anja ThiemeAnja Thieme
Anja Thieme
Recent advances in AI combine large language models (LLMs) with vision encoders that bring forward unprecedented technical capabilities to leverage for a wide range of healthcare applications. Focusing on the domain of radiology, vision-language models (VLMs) achieve good performance results for tasks such as generating radiology findings based on a patient’s medical image, or answering visual questions (e.g., “Where are the nodules in this chest X-ray?”). However, the clinical utility of potential applications of these capabilities is currently underexplored. We engaged in an iterative, multidisciplinary design process to envision clinically relevant VLM interactions, and co-designed four VLM use concepts: Draft Report Generation, Augmented Report Review, Visual Search and Querying, and Patient Imaging History Highlights. We studied these concepts with 13 radiologists and clinicians who assessed the VLM concepts as valuable, yet articulated many design considerations. Reflecting on our findings, we discuss implications for integrating VLM capabilities in radiology, and for healthcare AI more generally.

1 January 2015
Verified
Conference Paper
Closed access
HSHarshita Sharma
Harshita Sharma
NZNorman Zerbe
Norman Zerbe
DHDaniel Heim
Daniel Heim
SWStephan Wienert
Stephan Wienert
HBHans-Michael Behrens
Hans-Michael Behrens
PHPeter Hufnagl
Peter Hufnagl
The SCITEPRESS Digital Library offers online access to all papers presented at INSTICC conferences, as well as a few conferences organized by others.

1 April 2021 in Medical Image Analysis
Verified
Journal Article
Open access
HSHarshita Sharma
Harshita Sharma
LDLior Drukker
Lior Drukker
PCPierre Chatelain
Pierre Chatelain
RDRichard Droste
Richard Droste
APAris T. Papageorghiou
Aris T. Papageorghiou
JNJ. Alison Noble
J. Alison Noble
Ultrasound is a widely used imaging modality, yet it is well-known that scanning can be highly operator-dependent and difficult to perform, which limits its wider use in clinical practice. The literature on understanding what makes clinical sonography hard to learn and how sonography varies in the field is sparse, restricted to small-scale studies on the effectiveness of ultrasound training schemes, the role of ultrasound simulation in training, and the effect of introducing scanning guidelines and standards on diagnostic image quality. The Big Data era, and the recent and rapid emergence of machine learning as a more mainstream large-scale data analysis technique, presents a fresh opportunity to study sonography in the field at scale for the first time. Large-scale analysis of video recordings of full-length routine fetal ultrasound scans offers the potential to characterise differences between the scanning proficiency of experts and trainees that would be tedious and time-consuming to do manually due to the vast amounts of data. Such research would be informative to better understand operator clinical workflow when conducting ultrasound scans to support skills training, optimise scan times, and inform building better user-machine interfaces. This paper is to our knowledge the first to address sonography data science, which we consider in the context of second-trimester fetal sonography screening. Specifically, we present a fully-automatic framework to analyse operator clinical workflow solely from full-length routine second-trimester fetal ultrasound scan videos. An ultrasound video dataset containing more than 200 hours of scan recordings was generated for this study. We developed an original deep learning method to temporally segment the ultrasound video into semantically meaningful segments (the video description). The resulting semantic annotation was then used to depict operator clinical workflow (the knowledge representation). Machine learning was applied to the knowledge representation to characterise operator skills and assess operator variability. For video description, our best-performing deep spatio-temporal network shows favourable results in cross-validation (accuracy: 91.7%), statistical analysis (correlation: 0.98, p < 0.05) and retrospective manual validation (accuracy: 76.4%). For knowledge representation of operator clinical workflow, a three-level abstraction scheme consisting of a Subject-specific Timeline Model (STM), Summary of Timeline Features (STF), and an Operator Graph Model (OGM), was introduced that led to a significant decrease in dimensionality and computational complexity compared to raw video data. The workflow representations were learnt to discriminate between operator skills, where a proposed convolutional neural network-based model showed most promising performance (cross-validation accuracy: 98.5%, accuracy on unseen operators: 76.9%). These were further used to derive operator-specific scanning signatures and operator variability in terms of type, order and time distribution of constituent tasks.