Saverio Bettuzzi is a full Professor of Biochemistry at the University of Parma and Board Member of the INBB of Rome. He cloned and identified Clusterin (CLU) as the major over-expressed gene during castration-induced involution of rat prostate. His research team focused on the biological role of CLU as a tumour suppressor for prostate, colon, ovarian, lung cancers and neuroblastoma, discovered a gene signature for the prognosis of prostate cancer (PCa), and studied the anti-cancer activity of green tea extracts (GTE) and EGCG, showing that the progression of PCa can be blocked with GTE in mouse models and humans.