Land cover mapping of large areas is challenging due to the significant volume of satellite data to acquire and process, as well as the lack of spatial continuity due to cloud cover. Temporal aggregation—the use of metrics (i.e., mean or median) derived from satellite data over a period of time—is an approach that benefits from recent increases in the frequency of free satellite data acquisition and cloud-computing power. This enables the efficient use of multi-temporal data and the exploitation of cloud-gap filling techniques for land cover mapping. Here, we provide the first formal comparison of the accuracy between land cover maps created with temporal aggregation of Sentinel-1 (S1), Sentinel-2 (S2), and Landsat-8 (L8) data from one-year and test whether this method matches the accuracy of traditional approaches. Thirty-two datasets were created for Wales by applying automated cloud-masking and temporally aggregating data over different time intervals, using Google Earth Engine. Manually processed S2 data was used for comparison using a traditional two-date composite approach. Supervised classifications were created, and their accuracy was assessed using field-based data. Temporal aggregation only matched the accuracy of the traditional two-date composite approach (77.9%) when an optimal combination of optical and radar data was used (76.5%). Combined datasets (S1, S2 or S1, S2, and L8) outperformed single-sensor datasets, while datasets based on spectral indices obtained the lowest levels of accuracy. The analysis of cloud cover showed that to ensure at least one cloud-free pixel per time interval, a maximum of two intervals per year for temporal aggregation were possible with L8, while three or four intervals could be used for S2. This study demonstrates that temporal aggregation is a promising tool for integrating large amounts of data in an efficient way and that it can compensate for the lower quality of automatic image selection and cloud masking. It also shows that combining data from different sensors can improve classification accuracy. However, this study highlights the need for identifying optimal combinations of satellite data and aggregation parameters in order to match the accuracy of manually selected and processed image composites.

Anopheles mosquitoes are the vectors of human malaria, a disease responsible for a significant burden of global disease and over half a million deaths in 2020. Here, methods using a time series of cost-free Earth Observation (EO) data, 45,844 in situ mosquito monitoring captures, and the cloud processing platform Google Earth Engine are developed to identify the biogeographical variables driving the abundance and distribution of three malaria vectors—Anopheles gambiae s.l., An. funestus, and An. paludis—in two highly endemic areas in the Democratic Republic of the Congo. EO-derived topographical and time series land surface temperature and rainfall data sets are analysed using Random Forests (RFs) to identify their relative importance in relation to the abundance of the three mosquito species, and they show how spatial and temporal distributions vary by site, by mosquito species, and by month. The observed relationships differed between species and study areas, with the overall number of biogeographical variables identified as important in relation to species abundance, being 30 for An. gambiae s.l. and An. funestus and 26 for An. paludis. Results indicate rainfall and land surface temperature to consistently be the variables of highest importance, with higher rainfall resulting in greater mosquito abundance through the creation of pools acting as mosquito larval habitats; however, proportional coverage of forest and grassland, as well as proximity to forests, are also consistently identified as important. Predictive application of the RF models generated monthly abundance maps for each species, identifying both spatial and temporal hot-spots of high abundance and, by proxy, increased malaria infection risk. Results indicate greater temporal variability in An. gambiae s.l. and An. paludis abundances in response to seasonal rainfall, whereas An. funestus is generally more temporally stable, with maximum predicted abundances of 122 for An. gambiae s.l., 283 for An. funestus, and 120 for An. paludis. Model validation produced R² values of 0.717 for An. gambiae s.l., 0.861 for An. funestus, and 0.448 for An. paludis. Monthly abundance values were extracted for 248,089 individual buildings, demonstrating how species abundance, and therefore biting pressure, varies spatially and seasonally on a building-to-building basis. These methods advance previous broader regional mosquito mapping and can provide a crucial tool for designing bespoke control programs and for improving the targeting of resource-constrained disease control activities to reduce malaria transmission and subsequent mortality in endemic regions, in line with the WHO’s ‘High Burden to High Impact’ initiative. The developed method was designed to be widely applicable to other areas, where suitable in situ mosquito monitoring data are available. Training materials were also made freely available in multiple languages, enabling wider uptake and implementation of the methods by users without requiring prior expertise in EO.

Purpose: Radiotherapy imposes a significant physiological and psychological burden on gynaecological cancer patients. Prehabilitation is being increasingly used to prepare individuals for cancer treatment and improve their well-being and resilience. Whilst prehabilitation has demonstrated benefit for individuals undergoing cancer surgery, the structure, role and implementation of prehabilitation prior to radiotherapy are poorly defined and relatively unexplored. This scoping review aims to provide a comprehensive overview of the current literature regarding prehabilitation interventions for individuals with gynaecological cancer undergoing radiotherapy. Methods: This review was conducted following the gold-standard Joanna Briggs Institute guidelines for scoping reviews. Literature searches were completed in October 2024 across: the Allied and Complementary Medicine Database; British Nursing Index; Cumulative Index to Nursing and Allied Health Literature; Cochrane library (Controlled trials and systematic reviews); Embase; Medical Literature Analysis and Retrieval System Online; and the Psychological Information Database. Grey literature searches were conducted via Google Scholar, Overton.io, and Trip Pro Medical Database. Results: Ninety records met the inclusion criteria, pertaining to 56 studies. Cervical cancer was the most represented gynaecological cancer type across studies. A small number of multimodal prehabilitation studies were identified (n = 4). Studies evaluating unimodal interventions were more common, with nutritional interventions (n = 24) being the most frequent, followed by psychological (n = 22) and physical exercise (n = 6) interventions. There was considerable variation across studies in respect to intervention initiation, duration, delivery and outcome measures. Conclusions: The physiological and psychological impacts of cancer diagnosis and treatment are closely entwined. Further development of multimodal prehabilitation to cohesively address these is an important area for future research. Studies evaluating exercise interventions are relatively unexplored in this patient population and the potential barriers to engagement must be considered. Future research should focus on complete and transparent reporting of interventions, with input from those with lived experience, and adopting a standardised set of outcome measures reported across all trials.